ID U5VTF0_9ACTN Unreviewed; 340 AA.
AC U5VTF0;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=Autoinducer 2 import system permease protein LsrC {ECO:0000256|ARBA:ARBA00039382};
GN ORFNames=AFR_03260 {ECO:0000313|EMBL:AGZ38941.1};
OS Actinoplanes friuliensis DSM 7358.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1246995 {ECO:0000313|EMBL:AGZ38941.1, ECO:0000313|Proteomes:UP000017746};
RN [1] {ECO:0000313|EMBL:AGZ38941.1, ECO:0000313|Proteomes:UP000017746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7358 {ECO:0000313|EMBL:AGZ38941.1,
RC ECO:0000313|Proteomes:UP000017746};
RX PubMed=24637369; DOI=10.1016/j.jbiotec.2014.03.011;
RA Ruckert C., Szczepanowski R., Albersmeier A., Goesmann A., Fischer N.,
RA Steinkamper A., Puhler A., Biener R., Schwartz D., Kalinowski J.;
RT "Complete genome sequence of the actinobacterium Actinoplanes friuliensis
RT HAG 010964, producer of the lipopeptide antibiotic friulimycin.";
RL J. Biotechnol. 178:41-42(2014).
CC -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC autoinducer 2 (AI-2) import. Probably responsible for the translocation
CC of the substrate across the membrane. {ECO:0000256|ARBA:ARBA00025439}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC (LsrB). {ECO:0000256|ARBA:ARBA00011262}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP006272; AGZ38941.1; -; Genomic_DNA.
DR RefSeq; WP_023357884.1; NC_022657.1.
DR AlphaFoldDB; U5VTF0; -.
DR STRING; 1246995.AFR_03260; -.
DR KEGG; afs:AFR_03260; -.
DR PATRIC; fig|1246995.3.peg.656; -.
DR eggNOG; COG1172; Bacteria.
DR HOGENOM; CLU_028880_0_1_11; -.
DR OrthoDB; 9808136at2; -.
DR Proteomes; UP000017746; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06579; TM_PBP1_transp_AraH_like; 1.
DR InterPro; IPR001851; ABC_transp_permease.
DR PANTHER; PTHR32196; ABC TRANSPORTER PERMEASE PROTEIN YPHD-RELATED-RELATED; 1.
DR PANTHER; PTHR32196:SF29; AUTOINDUCER 2 IMPORT SYSTEM PERMEASE PROTEIN LSRC; 1.
DR Pfam; PF02653; BPD_transp_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000017746};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 340 AA; 35020 MW; 5DFB58F502203931 CRC64;
MTTAVASKPK RPQFSLGGVL KTRELGIVVA LAVLVAYTAI SNPRFLSGQS VRDILLNTAI
IAVMAAGQAV VVITRNIDLS VGSVLGLSAF TVATMMSANP GLPMVVALLV GLAVGGAAGL
LNGVLVRYGR VPALVVTLGT MYIFRGLTYS WAGGQQVNAD ELPRHFLQFA NASFLKIPWL
VLIALIVVGG VSLVMRNYRV GRELYAMGSS PQAAELAGIK VSRNLLGAFI VSGALAGLAG
VLFAARFGTV DAAAGTGYEL NVVAAVVVGG VAVFGGSGTV WGAGLGALLL TVIGSALTVL
DINQFWQQAI VGALIILAIC ADRLVAVRIA RSLRKKDSHV
//
