ID   U5W1C3_9ACTN            Unreviewed;       208 AA.
AC   U5W1C3;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   RecName: Full=VTT domain-containing protein {ECO:0000259|Pfam:PF09335};
GN   ORFNames=AFR_17115 {ECO:0000313|EMBL:AGZ41701.1};
OS   Actinoplanes friuliensis DSM 7358.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=1246995 {ECO:0000313|EMBL:AGZ41701.1, ECO:0000313|Proteomes:UP000017746};
RN   [1] {ECO:0000313|EMBL:AGZ41701.1, ECO:0000313|Proteomes:UP000017746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 7358 {ECO:0000313|EMBL:AGZ41701.1,
RC   ECO:0000313|Proteomes:UP000017746};
RX   PubMed=24637369; DOI=10.1016/j.jbiotec.2014.03.011;
RA   Ruckert C., Szczepanowski R., Albersmeier A., Goesmann A., Fischer N.,
RA   Steinkamper A., Puhler A., Biener R., Schwartz D., Kalinowski J.;
RT   "Complete genome sequence of the actinobacterium Actinoplanes friuliensis
RT   HAG 010964, producer of the lipopeptide antibiotic friulimycin.";
RL   J. Biotechnol. 178:41-42(2014).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU367016};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU367016}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the DedA family. {ECO:0000256|ARBA:ARBA00010792,
CC       ECO:0000256|RuleBase:RU367016}.
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DR   EMBL; CP006272; AGZ41701.1; -; Genomic_DNA.
DR   AlphaFoldDB; U5W1C3; -.
DR   STRING; 1246995.AFR_17115; -.
DR   KEGG; afs:AFR_17115; -.
DR   PATRIC; fig|1246995.3.peg.3472; -.
DR   eggNOG; COG0586; Bacteria.
DR   HOGENOM; CLU_044208_6_3_11; -.
DR   Proteomes; UP000017746; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR032818; DedA.
DR   InterPro; IPR032816; VTT_dom.
DR   PANTHER; PTHR30353; INNER MEMBRANE PROTEIN DEDA-RELATED; 1.
DR   PANTHER; PTHR30353:SF15; INNER MEMBRANE PROTEIN YABI; 1.
DR   Pfam; PF09335; SNARE_assoc; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU367016};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU367016};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017746};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU367016};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU367016}.
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367016"
FT   TRANSMEM        58..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367016"
FT   TRANSMEM        113..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367016"
FT   TRANSMEM        143..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367016"
FT   TRANSMEM        175..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367016"
FT   DOMAIN          39..163
FT                   /note="VTT"
FT                   /evidence="ECO:0000259|Pfam:PF09335"
SQ   SEQUENCE   208 AA;  20990 MW;  3093A7B7F7B6A441 CRC64;
     MNAASSFVGW LATLDEWSVL LFTFLSTAVE MTFLLGLLVP GEAVVMLAAA LPSGPLGFAL
     AVTVGTAGAL AGQILGYAVG RGFGARLRTT RLGRRIGVER FDRAEAYLAE RGAAALVAVR
     FVAVIHAVVP IAAGVARMPF GRFLGWSALG TLLWVGAFAG VGAATAGAGA GGGTALLLTA
     LGATCLGAVP IGARLLRRSF SHVSAVHG
//