ID   U6G8N7_9EIME            Unreviewed;      1046 AA.
AC   U6G8N7;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=PI3K/PI4K catalytic domain-containing protein {ECO:0000259|Pfam:PF00454};
GN   ORFNames=EPH_0004030 {ECO:0000313|EMBL:CDI74989.1};
OS   Eimeria praecox.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX   NCBI_TaxID=51316 {ECO:0000313|EMBL:CDI74989.1};
RN   [1] {ECO:0000313|EMBL:CDI74989.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDI74989.1};
RA   Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA   Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA   Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA   Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA   Tomley F., Pain A.;
RT   "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDI74989.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDI74989.1};
RA   Aslett M.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the PI3/PI4-kinase family. Type II PI4K
CC       subfamily. {ECO:0000256|ARBA:ARBA00008941}.
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DR   EMBL; HG690643; CDI74989.1; -; Genomic_DNA.
DR   AlphaFoldDB; U6G8N7; -.
DR   EnsemblProtists; CDI74989; CDI74989; EPH_0004030.
DR   VEuPathDB; ToxoDB:EPH_0004030; -.
DR   OrthoDB; 1699at2759; -.
DR   InterPro; IPR044571; P4KG1-8.
DR   InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR   PANTHER; PTHR45800; PHOSPHATIDYLINOSITOL 4-KINASE GAMMA; 1.
DR   PANTHER; PTHR45800:SF11; PI3K_PI4K CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00454; PI3_PI4_kinase; 1.
PE   3: Inferred from homology;
FT   DOMAIN          169..497
FT                   /note="PI3K/PI4K catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00454"
FT   REGION          656..699
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          727..895
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          976..1046
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        733..770
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        976..1025
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1046 AA;  113818 MW;  3004AD5EE85802FD CRC64;
     MPAVEGPAAA GGAGGGGGVM MLPSHPLYYF STHNALRGAD GDDLHFRVCF EELHGSRSCE
     LDVYPFYDVQ MVKRLLIKKL RLPASMQVKD VRLIFRGSEL PNWRPMTVFF ENPVKRLLWA
     VRGGSAQASI RPFARSQTFR SKELLRILEE VRLGFRRNVA PKLTMDGTGG TYILFDGRRR
     PVAVFKPEDE EAFAPCNPRG YEGRLGQQGL RGGVLSGEGA GREFAAYLLD ASYGGFAGVP
     ATMMVEACHP AFCSKGQIEV DGDVMMSTYV RSESSPSVSW KVGSFQAFVE AKECVGNFDA
     RLFSVGDVHR IAIFDLRVMN LDRNDSNILV APVVGYQKEA SAGSSSRSLR ASDGVVKQIQ
     SKLLRSVSAV GSCGTQLCVA DKAAVAGAET AATAASGVLT PDGKPTKWSN RRFRLIPIDH
     GMILTDVLDV ATLDLVWFDW PQSKEPYSES ELRLIYSFDV DKDLERLSRR VALRDNCLRT
     LRLATKLLQI CARHHLTVRE TATIAVRDDF DIPSPLEHLI RRSLEISYLA LDSTSLMSTN
     RLGFGIMDLA ELQGDPGKQQ GRRTSFEAKL KKAFKKKKRG GDEGPAEETA VEANGVCSRC
     GGFVSAAGAG ATTPRGSISV SCTVPSTVDV DGEVDSEDLE ERPLVRSCTT IEAWSDARSP
     VGAHTEGDGS SESGEPLNTA AGAVPRAAAH QPEDAEGLAP VGGAVNAECE RQTGGAIAPC
     RCGERMERRS SSSMGDSADS TSDSDLSSNS LTTSSNDGTH SSWTSSHSDE DSSKSASEPE
     ERLAPPTFGS FQAPGAAGGP LRHLPSAALF RYPSGEPRLS GRRKRRTSRN RRRKAETETE
     TKTDDAATSG PSPPRNEPDV FGNRHTKGTI RRLNGTARGT GCRPKKQPSA TTSTWSLTDS
     SGRVILLDWR DGRLEKLFFE VYESLLRQHI LHNHPQWFTY PYNGEAIERS ERRQQTFRRE
     ESSTLVTPLV AAPTVQGNSQ QVNATNTHRR LSSEASDDAT ANATGHQSTH KHIRSVQQPQ
     PQSPRQHEDR APAASRQTRF NISSDA
//