ID U6G8Q4_9EIME Unreviewed; 2206 AA.
AC U6G8Q4;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=ABC transporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=EPH_0006550 {ECO:0000313|EMBL:CDI75907.1};
OS Eimeria praecox.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=51316 {ECO:0000313|EMBL:CDI75907.1};
RN [1] {ECO:0000313|EMBL:CDI75907.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDI75907.1};
RA Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA Tomley F., Pain A.;
RT "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDI75907.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDI75907.1};
RA Aslett M.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; HG691204; CDI75907.1; -; Genomic_DNA.
DR EnsemblProtists; CDI75907; CDI75907; EPH_0006550.
DR VEuPathDB; ToxoDB:EPH_0006550; -.
DR OrthoDB; 6951at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF36; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 5 ISOFORM X1; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF13405; EF-hand_6; 1.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00054; EFh; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 83..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 557..576
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 596..624
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 630..655
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 667..690
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1160..1180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1333..1356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1376..1402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1414..1435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1441..1463
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1475..1497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1524..1545
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 736..975
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1727..1960
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 2048..2083
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1064..1086
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1651..1691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1065..1080
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1651..1675
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2206 AA; 246003 MW; 2CFFB2C1ABA60CC6 CRC64;
MGEREALNAA QEDNRENLDA QSYPSFVLTD CPALEPTEAS QQLRKTPRFR RAFFRRAAEL
AAATDRITVL LWRAFMFRLR YPIMTLIGLL VPAPLVSTVA LVASACTILA HYQDVEFNYI
PTNMTSTRHM VCNFAAYRNR TSNMKMASIP TSYWELYQVL FSVFNTVNAL KYADLCTTPS
SLMGSFGRRY DGLHLMYLPA ILHYGGFLAF VDKDGTDCQQ LRIFMEKFVH TVAPYLMKKT
TVGDLFKTFP SEKALDKYRR AAAAEKKRPI HSAFVCRAAG RGQLDVTIRM HVRRGTPRSF
ANDSVKFLRR HYTSYNSTTY FGGASFLLEA DVIGTPNEGK PYGHLTGGFL DLLTLAHVFN
LDRTKVRQLP AGSPVSPEFQ PQWERTSEAF YKMFDYFGRI PVLDSVAFSR NRKGLFRSFV
GEAEHHLAQM LALVICISAA NDQETPSGLS EVYRHLLPAW LLGPGYGVVR LFTRRAAATG
CDPDTPSMQL LERVFYSRTQ KMGIDLIMAA VGPLQGMLRN VSGPMRRAYS PFNFLESAMP
FVPATVISRS GKPHSCAAPF VVLFVCILWQ VVKAIMVDKE TGFKNMLKIL GISDRVLWTS
WYLFFTLYNL PTLVAVAFIS QYFAFTLSDI WFIILLFMLA LVASISFALF VTALFTDGNL
AAWNPHLQRV FMVACPAAAL GVGIDIAWIF NEPYIGGIRS STLKRPPKIQ QEARETSENP
FYVDSKGGEE DNKPLLEVRG VHKNFRTWKT KKCSRGSVQA VRGVSFSVYR DEIFGLLGQN
GAGKSTLISV ITGSFAATSG DVLIDGVSVR QHPSHARCNI GYCPQFDVLL PYLTIEETLW
LYAALRGIPR RRRTEEVAEL MSMMKLSEMA KVQVVALSGG WRRRVSSSVA FLGDPNIVFL
DEPTAGMDIL YRRTFWDSVR GLSKGRCIVL ITHMMEEADY LCDRLAIMVD GVIASEGTAL
TLKSRFGSGY IISVILRKQG EREEQRANRK LRQLLRAFEH PPTIAEVSRH ELRIVCPFSH
SFQLPRLFSE LEMNAQNYGI ESAVLGFASL EEVFLNVVKL AKGRDPESAG TDKEKGRSRS
RAAPSLGAAR DVVSINAMPT PANERCLSTA CRVPALPDNG RAQRPAQSTR HGPASASQSL
NIRVIRALVA KRIRLLYRDW ALVTVSFFIP LILMGLTLYL RSEKSEPRVP LTGQQLYEYR
LPKSIHSEVP YGGRGWMLGA LDQCYSPFMT HRNVSENVKN NNDMYEFLLG GYFGPHFPRF
GAYVTPEGQA DISDEASQLE VTIWHNSTFR DAIPLHYSHL VNCIAQARTG TWNAVFASNQ
PFEDTDDKSL DGLVVGFFTV IAYSFVAAGV GKVCIVERVR KVRHQQILAQ VTPFQYWISS
YIVDMVLLLL PCSIIFGMML WVDITPLVGP HQRGAFLLGT VLFCFSVCPL GYAISMGLDS
AMTFVIVMLL LGWSLPSIQA LFTEVSGLQG MYSQYLRYIF MLLPHAALCE LLTNLAMMNQ
LTGGDVKAKE LVNWMEFSKT GCPLLYLGLT ILLNWMICIV VDCAINYPMS RARVLASLSK
FVVSLVRFAG SCLCCPCSLC LSCLPNRNGN SQAGLRSGVP AETSRKTGLR ATRANNDGVL
FRSRNTNGIM GLNVQEEETR AATEVQQLRR RCRNPESSFS IDSHLHSEDF DRGEQETQNP
PSTAVPPGAA DGGQLPLVVH RLGKTYPPPI LQRCFCCFCP RSWSRKLPFC SGCKRPQPTQ
ALKGVSFCVP RGSCFAYIGI NGSGKSTTFN IIGSLMPQST GSVFIGGYDA LQQAQKARAK
LRYCPQTDAL LPTLTGAEHV YLYGCLLGLR RHQLRDFCAD FFDVIGCKKY MHTLVKSYSG
GTKRKLSLGI AMLGEVDLLL LDEPTSGVDP ESRQVLWRMI EEAKNCQTSG KAIVLTSHSM
EECEVLGDRV GIIHKGKMLC LGTPAELRSA YGHGYQIECV FVAAAVSRDP SLPRRFISVL
QKTLPTLHVL HRMAYKVTAS VAKGAVSLAT IFCEVEAAKA RFAVEAYVVS ETTLEEVFVE
VSLRADGKRR QELRVAFHAF DKNKTGKLDI NEMKYLLKSI GVCLSRREQK ALEAEYADRG
EFDYEDLLTL GQVVYNDVAI ERALVLALRK LTPKGAKTVS RTVLRDMLLN LGMGVKLTEE
QVDMFLDICC SEDGKRSDEI QISTFIYRQV LVLLILASLH AEVLRD
//
