ID U6IVP6_ECHGR Unreviewed; 350 AA.
AC U6IVP6;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=HSPB1-associated protein {ECO:0000313|EMBL:EUB63698.1, ECO:0000313|WBParaSite:EgrG_000825700};
DE SubName: Full=Heat shock proteinB1 associated protein 1 {ECO:0000313|EMBL:CDS15851.1};
GN Name=EGR_01321 {ECO:0000313|WBParaSite:EgrG_000825700};
GN ORFNames=EGR_01321 {ECO:0000313|EMBL:EUB63698.1}, EgrG_000825700
GN {ECO:0000313|EMBL:CDS15851.1};
OS Echinococcus granulosus (Hydatid tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC Echinococcus granulosus group.
OX NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB63698.1, ECO:0000313|Proteomes:UP000019149};
RN [1] {ECO:0000313|EMBL:EUB63698.1, ECO:0000313|Proteomes:UP000019149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24013640; DOI=10.1038/ng.2757;
RA Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y., Wang S.;
RT "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL Nat. Genet. 45:1168-1175(2013).
RN [2] {ECO:0000313|EMBL:CDS15851.1, ECO:0000313|Proteomes:UP000492820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23485966; DOI=10.1038/nature12031;
RA Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A., Sanchez-Flores A.,
RA Brooks K.L., Tracey A., Bobes R.J., Fragoso G., Sciutto E., Aslett M.,
RA Beasley H., Bennett H.M., Cai J., Camicia F., Clark R., Cucher M.,
RA De Silva N., Day T.A., Deplazes P., Estrada K., Fernandez C., Holland P.W.,
RA Hou J., Hu S., Huckvale T., Hung S.S., Kamenetzky L., Keane J.A., Kiss F.,
RA Koziol U., Lambert O., Liu K., Luo X., Luo Y., Macchiaroli N., Nichol S.,
RA Paps J., Parkinson J., Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M.,
RA Salinas G., Wasmuth J.D., Zamanian M., Zheng Y., Cai X., Soberon X.,
RA Olson P.D., Laclette J.P., Brehm K., Berriman M., Garciarrubio A.,
RA Bobes R.J., Fragoso G., Sanchez-Flores A., Estrada K., Cevallos M.A.,
RA Morett E., Gonzalez V., Portillo T., Ochoa-Leyva A., Jose M.V., Sciutto E.,
RA Landa A., Jimenez L., Valdes V., Carrero J.C., Larralde C.,
RA Morales-Montor J., Limon-Lason J., Soberon X., Laclette J.P.;
RT "The genomes of four tapeworm species reveal adaptations to parasitism.";
RL Nature 496:57-63(2013).
RN [3] {ECO:0000313|EMBL:CDS15851.1}
RP NUCLEOTIDE SEQUENCE.
RA Aslett M.;
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|WBParaSite:EgrG_000825700}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (OCT-2020) to UniProtKB.
CC -!- FUNCTION: May play a role in cellular stress response.
CC {ECO:0000256|ARBA:ARBA00037342}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; LK028576; CDS15851.1; -; Genomic_DNA.
DR EMBL; APAU02000005; EUB63698.1; -; Genomic_DNA.
DR AlphaFoldDB; U6IVP6; -.
DR STRING; 6210.U6IVP6; -.
DR EnsemblMetazoa; XM_024490570.1; XP_024354894.1; GeneID_36337036.
DR WBParaSite; EgrG_000825700; EgrG_000825700; EgrG_000825700.
DR OMA; CLVECID; -.
DR OrthoDB; 5401772at2759; -.
DR Proteomes; UP000019149; Unassembled WGS sequence.
DR Proteomes; UP000492820; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR InterPro; IPR041667; Cupin_8.
DR InterPro; IPR003347; JmjC_dom.
DR PANTHER; PTHR12461:SF43; HSPB1-ASSOCIATED PROTEIN 1; 1.
DR PANTHER; PTHR12461; HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED; 1.
DR Pfam; PF13621; Cupin_8; 1.
DR SMART; SM00558; JmjC; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51184; JMJC; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000019149};
KW Stress response {ECO:0000313|EMBL:CDS15851.1}.
FT DOMAIN 77..231
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
SQ SEQUENCE 350 AA; 39503 MW; 79251CBEFAE3C818 CRC64;
MNWSPDYLAE VIQENLSFRI GQRNANGLSP QWECDAHYVS TSVTDFVSWC RGNNTLAFGE
YPQNEWWAYA AYLHMGTTPA LSSLQKDVPW NSIFPYLPNP NGSTFWLGTN QSHTGCHYDT
YGVNFVLQVF GKKRWILFPP TDTPFLYPTR LPLEESTVFS RVNFKCPNFV KYPLILSAHP
RVVTLQSGDI LFVPRHWWHF VETVEEDISC AVNLWIDQPQ LDNTVRCKEA LTQLACFSLA
QCAPGNSGII NRLHAAERAF ARSENWFNCL VECIDAHISS VPLTRSSAPQ ITSGPVLDWS
ILSATDIVDI LPDSNKLPLP SGSFEVNLEK IIAAFLHPDV IDLVYSKLGE
//
