ID U6J1R4_ECHGR Unreviewed; 382 AA.
AC U6J1R4;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Alpha-parvin {ECO:0000313|EMBL:EUB64818.1, ECO:0000313|WBParaSite:EgrG_000805600};
DE SubName: Full=Beta parvin {ECO:0000313|EMBL:CDS15653.1};
GN ORFNames=EGR_00087 {ECO:0000313|EMBL:EUB64818.1,
GN ECO:0000313|WBParaSite:EgrG_000805600}, EgrG_000805600
GN {ECO:0000313|EMBL:CDS15653.1};
OS Echinococcus granulosus (Hydatid tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC Echinococcus granulosus group.
OX NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB64818.1, ECO:0000313|Proteomes:UP000019149};
RN [1] {ECO:0000313|EMBL:EUB64818.1, ECO:0000313|Proteomes:UP000019149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24013640; DOI=10.1038/ng.2757;
RA Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y., Wang S.;
RT "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL Nat. Genet. 45:1168-1175(2013).
RN [2] {ECO:0000313|EMBL:CDS15653.1, ECO:0000313|Proteomes:UP000492820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23485966; DOI=10.1038/nature12031;
RA Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A., Sanchez-Flores A.,
RA Brooks K.L., Tracey A., Bobes R.J., Fragoso G., Sciutto E., Aslett M.,
RA Beasley H., Bennett H.M., Cai J., Camicia F., Clark R., Cucher M.,
RA De Silva N., Day T.A., Deplazes P., Estrada K., Fernandez C., Holland P.W.,
RA Hou J., Hu S., Huckvale T., Hung S.S., Kamenetzky L., Keane J.A., Kiss F.,
RA Koziol U., Lambert O., Liu K., Luo X., Luo Y., Macchiaroli N., Nichol S.,
RA Paps J., Parkinson J., Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M.,
RA Salinas G., Wasmuth J.D., Zamanian M., Zheng Y., Cai X., Soberon X.,
RA Olson P.D., Laclette J.P., Brehm K., Berriman M., Garciarrubio A.,
RA Bobes R.J., Fragoso G., Sanchez-Flores A., Estrada K., Cevallos M.A.,
RA Morett E., Gonzalez V., Portillo T., Ochoa-Leyva A., Jose M.V., Sciutto E.,
RA Landa A., Jimenez L., Valdes V., Carrero J.C., Larralde C.,
RA Morales-Montor J., Limon-Lason J., Soberon X., Laclette J.P.;
RT "The genomes of four tapeworm species reveal adaptations to parasitism.";
RL Nature 496:57-63(2013).
RN [3] {ECO:0000313|EMBL:CDS15653.1}
RP NUCLEOTIDE SEQUENCE.
RA Aslett M.;
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|WBParaSite:EgrG_000805600}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (OCT-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the parvin family.
CC {ECO:0000256|ARBA:ARBA00005666}.
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DR EMBL; LK028576; CDS15653.1; -; Genomic_DNA.
DR EMBL; APAU02000001; EUB64818.1; -; Genomic_DNA.
DR STRING; 6210.U6J1R4; -.
DR EnsemblMetazoa; XM_024489336.1; XP_024356014.1; GeneID_36335802.
DR WBParaSite; EgrG_000805600; EgrG_000805600; EgrG_000805600.
DR OMA; WSAEMIH; -.
DR OrthoDB; 1328998at2759; -.
DR Proteomes; UP000019149; Unassembled WGS sequence.
DR Proteomes; UP000492820; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd21222; CH_PARV_rpt2; 1.
DR CDD; cd21304; CH_PARVA_B_rpt1; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR028433; Parvin.
DR PANTHER; PTHR12114:SF4; GH23568P; 1.
DR PANTHER; PTHR12114; PARVIN; 1.
DR Pfam; PF00307; CH; 2.
DR PIRSF; PIRSF039131; Parvin; 1.
DR SMART; SM00033; CH; 2.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 2.
DR PROSITE; PS50021; CH; 2.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Reference proteome {ECO:0000313|Proteomes:UP000019149}.
FT DOMAIN 81..190
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 246..353
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
SQ SEQUENCE 382 AA; 43350 MW; 6A32557CA97DDA01 CRC64;
MNSPGLSGTG NESFFSKLET LRSRNKKKSK KEVEDLAAEG RKAMESALCS LAVEDPENYM
LEEGQERSII ERASMESMEV KELVASLISW INDELINHRI LVRNISDDLY DGQILQNLAE
KLANIKLEYP EVTQSEFGQM QRLKEVVATI NQILGVPESW AKDQWSAEMI HDKDVIAIIR
LLVALAKHFK VGIRLADGVF LTVIVVRKIN GILEYRYERK YLTEPSQSVP DLGPSSHPLD
YLPNRHLVPR LITCFVNEHL QKLNLQVKDL THDFSDGVRL ILLMGLLEGY FVPLHCYHLH
PTTDSMRLAN VRLAFELMRV AELSEPLERP EDIILGDTKA VLRLLYGLVS HYQYAHGGGD
AFADLQKITE DEALDRSPEF TA
//
