ID U6KDK1_9EIME Unreviewed; 740 AA.
AC U6KDK1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 08-NOV-2023, entry version 33.
DE SubName: Full=ATP-dependent RNA helicase, putative {ECO:0000313|EMBL:CDJ36110.1};
GN ORFNames=EMH_0033460 {ECO:0000313|EMBL:CDJ36110.1};
OS Eimeria mitis.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=44415 {ECO:0000313|EMBL:CDJ36110.1};
RN [1] {ECO:0000313|EMBL:CDJ36110.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ36110.1};
RA Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA Tomley F., Pain A.;
RT "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDJ36110.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ36110.1};
RA Aslett M.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HG735560; CDJ36110.1; -; Genomic_DNA.
DR AlphaFoldDB; U6KDK1; -.
DR VEuPathDB; ToxoDB:EMH_0033460; -.
DR OrthoDB; 351254at2759; -.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR013784; Carb-bd-like_fold.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR042942; Laforin.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR46864; LAFORIN; 1.
DR PANTHER; PTHR46864:SF1; LAFORIN; 1.
DR Pfam; PF00782; DSPc; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00195; DSPc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49452; Starch-binding domain-like; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:CDJ36110.1};
KW Helicase {ECO:0000313|EMBL:CDJ36110.1};
KW Hydrolase {ECO:0000313|EMBL:CDJ36110.1};
KW Nucleotide-binding {ECO:0000313|EMBL:CDJ36110.1}.
FT DOMAIN 1..168
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 574..738
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
FT DOMAIN 673..716
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 203..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 258..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..283
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..307
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..373
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 740 AA; 82642 MW; 533BC57D8781A1EE CRC64;
MRTWRLYVSY FLDVYTVGAC RKDVPGSKGS LLACLVLRHC CCYLWFCCPD VAILHGGMQQ
GDRLAVMRRM QHHFLGDSDS SRTPLVLVAT DVAARGLDFP PALSLVVCYD APHDPEVYVH
RVGRAGRAGR SGLAWSLLTK QEKRQAAFVV EKMETSGQTV PRSLLEFAMQ FRKHFYSLYM
TPFNGGCHTA GHSGYPVCGS TNKRGRWDSK EQSSSSNNSA NDESGTASGG SEGRRGALNF
AKREQRRQQW LSTLEARRDQ RQQLEQQQRN RHRRDRSPSP RRSFRERPQQ TPPVGQEERQ
RSQLGVSGSP EFLGCWDPSR CLPLLPYTTP TEGGMEPSLW FADVEVDEQR LGACRASATA
GSECNSAQRD SPKSPRDSFS DRLIAAVARK YSPLAGSMCS GSLPDMRRTT NDETSSVTAA
ATCRIDHRSP EIIAILDSHP LKSVQFEFKF ILWTPESPVA PYVPNTPGEP FQCVAYGSPF
CTWRTWLFPP PPAQRAVPPS KAMHVVWEGS GPSSNRKFCF DPMDVVVDEC ESGNLEVLYL
CKIARFEDPR ADSANEYGHT TRFYNTVKAE GRMDYSRILP NLYVGSCPRQ LKHIRQLKQD
LKVTAVFNLQ TTEDIKNNFP DPIASTRTPE AVGQLYESAG MRYVWMPTED MSDACRKLAV
AQCALVLDAL IRNGHTVYVH CNAGVGRSVA AVSAYLCFCV GIDQRKVNFL VSTRRPVAYW
DEKAIKAGLL DYQAKFGKAG
//
