ID U6KGZ2_EIMTE Unreviewed; 2372 AA.
AC U6KGZ2;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN ORFNames=ETH_00027680 {ECO:0000313|EMBL:CDJ37295.1};
OS Eimeria tenella (Coccidian parasite).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=5802 {ECO:0000313|EMBL:CDJ37295.1};
RN [1] {ECO:0000313|EMBL:CDJ37295.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ37295.1};
RA Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA Tomley F., Pain A.;
RT "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDJ37295.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ37295.1};
RA Aslett M.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR EMBL; HG673752; CDJ37295.1; -; Genomic_DNA.
DR RefSeq; XP_013228133.1; XM_013372679.1.
DR EnsemblProtists; CDJ37295; CDJ37295; ETH_00027680.
DR GeneID; 25254629; -.
DR VEuPathDB; ToxoDB:ETH2_1303200; -.
DR VEuPathDB; ToxoDB:ETH_00027680; -.
DR OMA; CLFRISL; -.
DR OrthoDB; 216771at2759; -.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR039190; TTC14.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR23184; TETRATRICOPEPTIDE REPEAT PROTEIN 14; 1.
DR PANTHER; PTHR23184:SF9; TETRATRICOPEPTIDE REPEAT PROTEIN 14; 1.
DR Pfam; PF00888; Cullin; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
FT DOMAIN 1750..2194
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 48..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 131..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 188..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 430..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 519..567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 611..648
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1047..1120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1453..1473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1494..1532
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1612..1717
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1871..1969
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2093..2134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2205..2235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..567
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1047..1077
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1087..1120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1453..1471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1657..1678
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1692..1717
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1876..1902
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1912..1969
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2372 AA; 253720 MW; 71ACA561AD003EB3 CRC64;
MFPKQEQKEQ RLVQQQREQQ EQQRERIAAA AAAAAAAPAA AILGSTCQLQ HGTGGSEGGE
RSSSSSRTRS SDMDRAAVAG GCSVAETRQE SAAATAAAAL GPPPRASSSK RRITGAVASV
AAAVASVSVA AADMSPRAGL RTTPRRRRPL RSSSSSSTVA AVTAAAAAAA VPAEQLAAKV
SSHRSVDSAA AAAADSPTHQ HFSRAARTRQ QQQLQQQQLQ QQQLQQQQLQ QQQLQQQQLQ
QQQLQQQQLQ QQQLQQQQLQ QQQLQQQQLQ QQQQQNGFDT TEVVYCALLS GAEDLAASPL
SGLEAAKQQQ QTPGVAETVA EAANAAETAA APVAAAAVGV VAAVGGSTVP QRLPVSAPET
AARAAALGFT AAPSAAAAAS TQGSSSSSRR ALRAASSHCL STPNDAAAAA AVAAGAAAAA
AAAAAAEGGE ATPTVRTESG RPAAAAAAAR KRLGAAAGHP SHSKRHRRQQ AAEQQQGNEP
APAAATCDDA AAAAGAAAVA APAAAPAASE GDRAEAQAAA SVVRLAPPES ESATAAAAPA
AAAEQPGTES LRDSSGSSSS SSSSSRGRRA AAAAAAAALQ SCAKKQRAAP CRCSGSTACS
CSSCSCCSSS SSSSSSNGGS TNVDAVGQVQ SSDNVGSSSS SSSSCASGSS SSRISATAAA
AAAAASAATA LPRSVAAVEA ISMLQQLWVR PVLQYAETLD PLLLPSRDHF AAAYSLVQQL
TETEETAFQV YCLFRISLAE WAAKQLRLIV QQQQQQQQQH AVAAARTAQQ VAPASAAAAA
AAVAAAAAAA AAGSSAPGVS LPERCCCADC RVAERDSSKC CRSSCPAGGA AAAGDRERAA
METRRPHGCL RCTGRQQQPP QQQQLQQQQA FPVQLHARRV LQQPLQQHRE DGLLCSCSAC
GTSLLQRLLR CWEVYGHLVY WLMRGFCYLD RFFTGRRKEI GDTPNLLLCA LAVFQTCVYA
QIHRRTVEAL TATVAGYRQQ LQQSQQQQQQ QLVLLQPQYH GIDPASFRKL MLMLCCLGEP
HIAALESFPA EAAAAAGAGA ECSAYNQAAQ QQPENSRALS DKIRSSSSSS NSGRSRAMRV
VQWRLLPSPQ SGDTSSVSAA ARRQQQTAAA QQQHAAAARQ QQTVAARQQH ITVAQRQSTV
TAQWQQAAAA QQHQQLSQQQ LQELQQGTVT RDHQQRVERQ QLRQQLQQHL LHQRHMQLQQ
QQQHHQPTGR FFDDLQHSML TESESYYCSK SREWLLQDLA AAPPEAQQQL LQQHHPQQRI
DFAAAADCAA AAAAATAQQQ RLHQRTRTLG TCWLRACCDS SAAAAAAAAR AAALPSAAAT
KEEDETVTVT VYCSCGSGTC CEGHSSSQQQ QQPRQLKLRV CEARLLRRLQ QQQTEVGLSC
SSYTERVHML LFGEQQVFKL AALWPRLQQN LLQKASKIAV MDCLHFVLCG PGGLTDLLQQ
HAFVNDLHAA PYQQGQSQQQ QQQQQQSEPV EETGWDVGGH GIWECSSSSG GGSSNACSSS
STSGSNLSFR PSSSECNASS SSSSSSSSSS SSGGVIDLCL LLKHRRLLLH SVWRLLRLYR
PTQQRQQKPR DLVAALVREA ISARVLQITE PLRTAAAVQA AAAAAAAAGS AAPGARAASP
TEKPQTRGAA SSEVAAAGAA AAAGAQTKAA ADPPSRRVTR SISSSSTSSG SKTGLLQQDL
PAGKSRGRGS VRVSSVKKQQ QQQTQLEQQQ QQQREEDWLE GPQGVACRRL LDFQGEVGRL
IDFVFKGDAR MVEVIGTAIR DALSHVSSLA ASLCLYWDRF LPRLQRYSQT KKVAAHLVAL
LQNMPDRAGF LEAYRRHLGD RLLLRGCRGI EQEKLIADLL ERHAGADLQA TVRIAAMPRD
IEASALLSRE FQQQQRQQEH QQRKQEQQQL DERQRQQTHQ MCMRHLRETV QISREQQQQQ
QRGRSSQRLQ QLQLQRQRQQ HQKEQQQLAK QHQQEQQEHN SQREQQAQQQ RLQQELLLQQ
LDDADETPEL LRLPYPQQQF SALILRWNCW AVEERQRDLR NSTQLLLPPQ LSQPIVSFTA
FYTGKYSSRV LAWQMHCSRV TFATSLYTPA TAATAAAAAA AVAVSEENSS NCIRRQSQRL
QPPPSQAARS CSSSSSCSRN SSKNPSSSNA CIKSPTATSS GPLVTLLETD PYAATILLLF
NDDARAARGI SLEEIEAETK FRPAEITEAA ASLLRPLPLL MLCPPGHLQG QAEEQEQRRG
QQQQQQQHEE DGRDRKAFAD DLEAKLAGGW LLRVNETFCS SSDSSSSSSS KWQYIRCCPA
LSLAAIAEAK QQKKETKVQS KKEEAPTSAA DKKILLEAAL VRILKREGSA DDAALAAAVL
GPTRTAAAEE QLQQALGSLV EREFLRRDEE NP
//
