ID   U6KIZ7_EIMTE            Unreviewed;      1378 AA.
AC   U6KIZ7;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=Histone deactylase, putative {ECO:0000313|EMBL:CDJ37879.1};
GN   ORFNames=ETH_00021920 {ECO:0000313|EMBL:CDJ37879.1};
OS   Eimeria tenella (Coccidian parasite).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX   NCBI_TaxID=5802 {ECO:0000313|EMBL:CDJ37879.1};
RN   [1] {ECO:0000313|EMBL:CDJ37879.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDJ37879.1};
RA   Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA   Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA   Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA   Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA   Tomley F., Pain A.;
RT   "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDJ37879.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDJ37879.1};
RA   Aslett M.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; HG673788; CDJ37879.1; -; Genomic_DNA.
DR   RefSeq; XP_013228717.1; XM_013373263.1.
DR   EnsemblProtists; CDJ37879; CDJ37879; ETH_00021920.
DR   GeneID; 25253499; -.
DR   VEuPathDB; ToxoDB:ETH2_1046400; -.
DR   VEuPathDB; ToxoDB:ETH_00021920; -.
DR   OMA; WLSNPFC; -.
DR   OrthoDB; 69755at2759; -.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   PANTHER; PTHR10625:SF4; HISTONE DEACETYLASE 6, ISOFORM G; 1.
DR   PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00850; Hist_deacetyl; 2.
DR   SMART; SM00248; ANK; 4.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF52768; Arginase/deacetylase; 2.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023}.
FT   REPEAT          265..297
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   DOMAIN          543..749
FT                   /note="Histone deacetylase"
FT                   /evidence="ECO:0000259|Pfam:PF00850"
FT   DOMAIN          823..1010
FT                   /note="Histone deacetylase"
FT                   /evidence="ECO:0000259|Pfam:PF00850"
FT   REGION          767..802
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1078..1133
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1145..1174
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1324..1354
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1078..1092
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1333..1347
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1378 AA;  144857 MW;  E0F532C92C4FD552 CRC64;
     MRPEADPDCP PVALGMADCA VFVSPQGGVS LARSTSSGSA PTAPHQPLLH LTGDVSCYRE
     GTLHRLIAAR NVPGVRQWLS NPFCRDTIND FNHAGETPLH VALHVCEPRI LSLLLNPPPV
     QMPPQCLLAC SSSSGGGGGE CVGVAPSGGG TSVHGEWAAD AANAAAAAAA ATVDFSLPLD
     DIPALHILVG RSSFAHVRAD AAECLRRLLH HVGLLHMTTG GSRVCSRCTF TSTSSRGSRS
     ISSGSCPPRV ECGLQELDLD ATDGSGKTAL HVAAAGGGAA AVELLLHAGA DPLIADKRGL
     LPLHVAVDSR SVGCLLLLLA HTFPEDCFYW CDKLEQQQQE RLVVGSSAEA ASVGECSDAR
     APKKVVLQRA ERRPLVHCAT SSSLVYRIAR RCVRRCSFRC LAALLSYPLV AACSGRSEPS
     SEAPESVMAL QLLHAQQLQE LVSLARRSGC LQLFLSTLSE LVDAEPSHSV AEAVIAEATG
     GRGPLQGPIT YVQQRCSRSG RCYRVPEAAG TLLATHESCM HHLPLPEPSD FPVKRFKLMQ
     RFPENPSRLE VLVHPSSGVL KAAEFRHLDW IDNAAPASLA DILRVHDVSY IFRLKQKIRS
     TFGTRSVNKS FSGSSSSSSY GGPSPVDQFA YSFADGDTPV TALSWEAATS AAGTVIAAVD
     AVCTGAKVNA FCAVRPPGHH LGSWGAAQTA PYALTDEDIA AGSQGFCVLN NVAIGAAYAR
     YNYAHRGIRR IAIVDFDAHH GNGTEQIMRN VGLKFRKLQG LSALLADGSS PAAGQRTHRE
     APWGPPSDSW EAEGARAPPE DGAALQDVPV QLPMWLGWRD ENDSEELFFA SIHAFDGNFY
     PGTGADCEDF GGPTILNVTM PVHGACSTPV EGSEGDPCCR CERCSEQSCI GPKPRGAHLG
     TAAADAACAS GDEGGYRCHH CRRPGLSPRS IRSRLLFKHR VLRRLEAFRP DLIFLSAGFD
     GHIKDPIGGE AVGWTEDDFH WLTMQVQRVA HRHCRGRCIS VLEGGYNVRG GSISPLALCV
     REHVRALVKA AHMQQEIDAH MQAQQAHAAA AEAHSQVHAK TVVGVHQEAR RLTAAGGLQS
     VAGSSGEESH QEGRLTPTPH PEGSDQLDQE GPWAEPDLSD YGSDSGFSSS EDETDAFLDE
     CEAADHESAV TEEEAEESGP SAAPVAPGNP YVTTSSQPPF CAGVTSQGHT VQPAAVPFIA
     SFEEVPQHSF GPTVGAATTY VHPPVPGDPC CKEHVVRTVL QPTVAAAAAG AGQWVGHEDQ
     RVFHTIQEGI TSPSAISSLS DDTAAASSGP DAAAAAAAAA QPAGGFLVGA PCLTGSVVSA
     AATGPPPLPH QQPSTVLATS TSASDAEASP RVEDHVAAEV GEPYSKAQRL QFLCGFPG
//