ID   U6KLY6_EIMTE            Unreviewed;       912 AA.
AC   U6KLY6;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Penicillin amidase domain-containing protein, putative {ECO:0000313|EMBL:CDJ38991.1};
GN   ORFNames=ETH_00029250 {ECO:0000313|EMBL:CDJ38991.1};
OS   Eimeria tenella (Coccidian parasite).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX   NCBI_TaxID=5802 {ECO:0000313|EMBL:CDJ38991.1};
RN   [1] {ECO:0000313|EMBL:CDJ38991.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDJ38991.1};
RA   Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA   Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA   Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA   Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA   Tomley F., Pain A.;
RT   "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDJ38991.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDJ38991.1};
RA   Aslett M.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S45 family.
CC       {ECO:0000256|ARBA:ARBA00006586}.
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DR   EMBL; HG674134; CDJ38991.1; -; Genomic_DNA.
DR   RefSeq; XP_013229746.1; XM_013374292.1.
DR   AlphaFoldDB; U6KLY6; -.
DR   MEROPS; S45.003; -.
DR   EnsemblProtists; CDJ38991; CDJ38991; ETH_00029250.
DR   GeneID; 25254943; -.
DR   VEuPathDB; ToxoDB:ETH2_1327500; -.
DR   VEuPathDB; ToxoDB:ETH_00029250; -.
DR   OMA; TINEAYW; -.
DR   OrthoDB; 201899at2759; -.
DR   GO; GO:0016811; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; IEA:InterPro.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.1400.10; -; 1.
DR   Gene3D; 2.30.120.10; -; 1.
DR   Gene3D; 3.60.20.10; Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1; 1.
DR   Gene3D; 1.10.439.10; Penicillin Amidohydrolase, domain 1; 1.
DR   InterPro; IPR029055; Ntn_hydrolases_N.
DR   InterPro; IPR014395; Pen/GL7ACA/AHL_acylase.
DR   InterPro; IPR043147; Penicillin_amidase_A-knob.
DR   InterPro; IPR023343; Penicillin_amidase_dom1.
DR   InterPro; IPR043146; Penicillin_amidase_N_B-knob.
DR   InterPro; IPR002692; S45.
DR   PANTHER; PTHR34218:SF4; ACYL-HOMOSERINE LACTONE ACYLASE QUIP; 1.
DR   PANTHER; PTHR34218; PEPTIDASE S45 PENICILLIN AMIDASE; 1.
DR   Pfam; PF01804; Penicil_amidase; 1.
DR   PIRSF; PIRSF001227; Pen_acylase; 2.
DR   SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT   REGION          241..262
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          886..912
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   912 AA;  102615 MW;  08C7945F24F0ABC5 CRC64;
     MPCDAVEVSG WSASRRVSLD PWDYYALTYT DFFSFVVGLI GRPVISRFFT PDEAFWNTPA
     EVPGIQSTIK IGHDKYGLPY LTASSQRPAQ IELLRLVATG KSAAVLGASM TDTDMITRTV
     ISEEALLWKL RKLPRHGVAC LIAYSRGKPR LSHKLQDPRL LLSGEHYFDF LTAPCRALMR
     GLTRDFVRVH LKESLGDKWK LFDFGFPEGV PPLNPEGSGP SLYDLEGKPV AFPSVELKDT
     EWSTRGPSAF PEITEGPHSL NPEFGGPMHD RDPSPKMTPE RMHQFKEDMQ RAEDFYDLKH
     PKPWTTEQQP QHSNTFSLKV DGSNGWAVSG KLTKTGMPLL AGDPHVEVNA PGFWMPMWLK
     SDGKLDGLPV RGVGATAVGT TGMFIGHNDY AAWTQTVAHT DIEDLFLVEL NEEGTHYYYG
     GKQYPLKFIE HNIYVKGRPN PIRHISRYSH HGPLFSDAVP PLRKRIGKNQ ALVLASVALR
     APLPVAWAEK MLFGKEWKDY IEMGQHAQMN EFVCIWATKD GAIGASVTGA VPVRPFSTIP
     QFRDGSDPKQ DWKGVLPQEQ IPFVMNPKSG IIVAGNSVLA DDPKRLFGEV FVPGHRVRRA
     HQLLADLKSK KEIEIQDLIK MQEDQYSEHG CEFKDFVLKE FLHRFDLKND QEEATALCAD
     EGLTPYVARL LTAAMESWDC SMNATSHGAS IYEVWLQMVL QGVFAANNWS DEALFSLVES
     GLLPAEYPLS RLLCKSATDT VKYLMGRLGP DVKDWHWGKL RSRYIDHLFV RDAPALRHLL
     SVGPLKWGGN FGTLKAHHFE PHILKADDPL TGNFHRGIDT TSLRVVFDLS NWENSLWAYY
     PGVSGWPGSK HYGDTAELLE DGKEKLMPIP WDEEKIEASL IATKILSPKQ ERQQAPQRSQ
     QPPRQQQQKQ EF
//