ID U6M9S1_EIMMA Unreviewed; 276 AA.
AC U6M9S1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=NAD binding domain of 6-phosphogluconate dehydrogenase, putative {ECO:0000313|EMBL:CDJ60962.1};
GN ORFNames=EMWEY_00008560 {ECO:0000313|EMBL:CDJ60962.1};
OS Eimeria maxima (Coccidian parasite).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=5804 {ECO:0000313|EMBL:CDJ60962.1};
RN [1] {ECO:0000313|EMBL:CDJ60962.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Weybridge {ECO:0000313|EMBL:CDJ60962.1};
RA Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA Tomley F., Pain A.;
RT "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDJ60962.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Weybridge {ECO:0000313|EMBL:CDJ60962.1};
RA Aslett M.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HG721967; CDJ60962.1; -; Genomic_DNA.
DR RefSeq; XP_013337612.1; XM_013482158.1.
DR AlphaFoldDB; U6M9S1; -.
DR EnsemblProtists; CDJ60962; CDJ60962; EMWEY_00008560.
DR GeneID; 25334842; -.
DR VEuPathDB; ToxoDB:EMWEY_00008560; -.
DR OMA; QFYADVQ; -.
DR OrthoDB; 203032at2759; -.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43060; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43060:SF15; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 2.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027}.
FT DOMAIN 12..99
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 138..253
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 144
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 276 AA; 28582 MW; 535191AAEF594017 CRC64;
MSSIEVIPGK TRIGWIGTGV MGRPMCENIL KKGFSLTVYN RTASKAAALQ QLGAAVAATA
AEVAAAVDVL CIMVGTPDDV QQLILGPGGV SSRLSPGDVG ARNGTLTVMA GGDAKTFENL
RPLFEAVGTN IIHAGPAGSG QRMKLCNQIT LCTNLVGLAE GLLFAERAGL DIEKTLAVLS
GGGAASWSVS TYGPRIRDGD FRPGFFVRHL VKDLRLALNE AARLKLALPG LGLALQLYQA
LEAQGGGSLG VHALKIALNN INAQNKSIED VVGQLN
//
