ID U6MX95_9EIME Unreviewed; 1457 AA.
AC U6MX95;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Dynein heavy chain 1, axonemal, related, related {ECO:0000313|EMBL:CDJ66340.1};
GN ORFNames=ENH_00019140 {ECO:0000313|EMBL:CDJ66340.1};
OS Eimeria necatrix.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=51315 {ECO:0000313|EMBL:CDJ66340.1};
RN [1] {ECO:0000313|EMBL:CDJ66340.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ66340.1};
RA Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA Tomley F., Pain A.;
RT "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDJ66340.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ66340.1};
RA Aslett M.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HG723552; CDJ66340.1; -; Genomic_DNA.
DR RefSeq; XP_013434808.1; XM_013579354.1.
DR GeneID; 25472087; -.
DR VEuPathDB; ToxoDB:ENH_00019140; -.
DR OrthoDB; 275566at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR PANTHER; PTHR45703:SF1; DYNEIN HEAVY CHAIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 192..301
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 478..618
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 822..973
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 1457 AA; 164237 MW; 64A836B8AA08E1CE CRC64;
MAFVKDLATA GRSVEIWMRD LEQIMKLSVK NALHQAITDY AKCERTTWVT KHAGQCVLNG
SQVHWTALVE DAIQTGQLKS LMEARTRQLL DLVALVRKGL NSMQSITIGA LIVIDVHAKD
IVQRLWDEEV SSVEAFEWIA QLRYYWRDDN CWTQCVQTDF PYGNEYLGNT SRLVITPLTD
MAYMTLMGAQ QLNLGGSLAG PAGTGKTETT KDLAKALATQ CVVFNCSEMM DYIMIAKFFK
GLVSSGAWCC FDEFNRINVE VLSVIAQQLI VLFGAKNQLQ GYDTTLEIDF EDSRIVVEPI
FNVFITMNPG YAGRTELPDN LKCLFRPMAM MVPDYSMIAE IMLYSFGFDQ ARELATKMVA
TFKLSSEQLS SQDHYDYGMR AVRSVINAAG ALKRKHSSMD EQQILLQALK DVNVPKFLSH
DLPLFENIIA DLFPGIEIPR SDNQLLQEAL ALQSEVLRLQ PVEAFMLKVM QLYDTVQVRH
GIMLVGPTGG GKTSSYRLLA AAMSDLHKVP GFAKVHVDVL NPKSVTIGQL YGCFNETTHE
WTDGLAAALI RHSIRDTSPD QHWIMFDGPV DALWIESMNS VLDDNKKLCL NSGEIIALTP
RMVIMFEVED LSVASPATVS RCGMVYMEPD VLGFRPLVAS WLKGLPPTFK DAHKTLIEEL
CDNIIAGGTV FIRKQCKEVI RTVNSNLCVS CLRMLGSICS RYRPVDKPAD SEQGDVLLSR
LPAAFIFSFV WSFGVAVDGP SRKKIDDWLQ NRVRELGFDI DLPAADSSFF DFCYDINSHR
WTHWEDTASS FVVPKGATYE NIVVPTLDSI RLSYSISTLL LNGHPVICPG PTGTGKTVVL
TELLLLSLPE NFEAHLMSFS AHTRVNQVQD LLEAKLEKRR RGVYGPAAGK TCIFFIDDLN
MPRKEEFGAQ PPLELLRQWF DHKGWYDRKA LAFQEVVDVA MVAAMGPPGG GRNEISARLL
RHYCVLAFNE LQRTSIAKIF QTLNKYCFQQ FPQNIQALTD PLVFATIDLY AEVTKALLPT
PMKSHYTFNM REIWKVFQGL SFLSPKVVNE PTAVVRCWIH EACRVFCDRL VDDEDRRWFH
ELLQQQAKQT FGVDFTDTKE ISSMIFADFV QHSSDRHYLE VASAEKLKRV VEDYLQDYNN
TFSVPMQLVM FGDACGHVTR ICRVLRQPSG HALLLGVRGS GRQSLSRLAA FIMETECFQI
DASKGYGISE WRDDLKTCFM KSGLEDKVQT FLFCDSQVLE ETMLEDINSA LNYGDAPNIY
KKEDNEEIMK VCRAYCKQLG MAPTKGNVFN AYVKKVKANL HMILAMSPLG VQFRTWLRMF
PSFTNCCTIN WFSEWPAEAL VSVAHMQMEK SDVVVQSYEQ VLNVLQAMHS GVQSTAARYR
EELGRTMYAT PTTFLEMLSA FLQLVQAKQV DLVTIQDRFE KGLGKLEETS KQVAAMQAQL
QELQPVLQAT SEEVGLL
//
