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Database: UniProt
Entry: U6MXV1_9EIME
LinkDB: U6MXV1_9EIME
Original site: U6MXV1_9EIME 
ID   U6MXV1_9EIME            Unreviewed;       444 AA.
AC   U6MXV1;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   25-APR-2018, entry version 18.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=ENH_00058300 {ECO:0000313|EMBL:CDJ68796.1};
OS   Eimeria necatrix.
OC   Eukaryota; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX   NCBI_TaxID=51315 {ECO:0000313|EMBL:CDJ68796.1, ECO:0000313|Proteomes:UP000030754};
RN   [1] {ECO:0000313|EMBL:CDJ68796.1, ECO:0000313|Proteomes:UP000030754}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDJ68796.1,
RC   ECO:0000313|Proteomes:UP000030754};
RA   Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA   Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA   Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA   Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA   Tomley F., Pain A.;
RT   "Genomic analysis of the causative agents of coccidiosis in
RT   chickens.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDJ68796.1, ECO:0000313|Proteomes:UP000030754}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDJ68796.1,
RC   ECO:0000313|Proteomes:UP000030754};
RA   Aslett M.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; HG725603; CDJ68796.1; -; Genomic_DNA.
DR   RefSeq; XP_013437263.1; XM_013581809.1.
DR   EnsemblProtists; CDJ68796; CDJ68796; ENH_00058300.
DR   GeneID; 25475971; -.
DR   Proteomes; UP000030754; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:proton transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000030754};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030754};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM     37     56       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    118    139       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    151    171       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    214    235       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    374    404       Helical. {ECO:0000256|RuleBase:RU361189}.
SQ   SEQUENCE   444 AA;  48529 MW;  9E937B6C88FC4B9D CRC64;
     MYGDIGHGAI VLLLGLFLLL RQQQLQQQRG LLAALLPYRY LLALMGLFAV YAGFLYNDLF
     ALGVDLFGSH WTEDGHETLN GAIRLRQLGE DPYPFGIDPA WKGASNELLM VNSVKMKLSI
     AIAVVHMGVG VLLKGLNFWF FGEVLSFCCE FVPQLLFLLL LIGYLNFLVV LKWVSPRSSN
     KPNLISSIIN MCMMGEVAAE DQLYQHQQTV ERVLLLLLLL TIPVMLLVKP AVLLLRSKRA
     AAAADKQQQQ QQQQQQQAPA AGHAALDAAE NGDAAAAAAA AAAGEAPAAG GAARPPQQQQ
     QQQQQQQQQQ QEEAAGAGDL FIFQMIETIE FVLGTVSNTA SYLRLWALSL AHQQLALVFY
     SQTVVRALTA AEDAAAAAAA AALFAAFAVF ACITFGVILC MDLLEVALHA LRLQWVEFQN
     KFYKGDGHKF EPLDFFLVVQ RKAT
//
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