ID U6N6B1_9EIME Unreviewed; 2265 AA.
AC U6N6B1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Dynein heavy chain {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=ENH_00068950 {ECO:0000313|EMBL:CDJ69450.1};
OS Eimeria necatrix.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=51315 {ECO:0000313|EMBL:CDJ69450.1};
RN [1] {ECO:0000313|EMBL:CDJ69450.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ69450.1};
RA Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA Tomley F., Pain A.;
RT "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDJ69450.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ69450.1};
RA Aslett M.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HG725730; CDJ69450.1; -; Genomic_DNA.
DR RefSeq; XP_013437917.1; XM_013582463.1.
DR GeneID; 25477028; -.
DR VEuPathDB; ToxoDB:ENH_00068950; -.
DR OrthoDB; 275566at2759; -.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10676:SF352; CYTOPLASMIC DYNEIN 2 HEAVY CHAIN 1; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12780; AAA_8; 2.
DR Pfam; PF12781; AAA_9; 2.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF18199; Dynein_C; 2.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 2..76
FT /note="Dynein heavy chain 3 AAA+ lid"
FT /evidence="ECO:0000259|Pfam:PF17857"
FT DOMAIN 172..222
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 298..501
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 561..879
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT DOMAIN 1178..1274
FT /note="Dynein heavy chain ATP-binding dynein motor region"
FT /evidence="ECO:0000259|Pfam:PF12781"
FT DOMAIN 1278..1365
FT /note="Dynein heavy chain ATP-binding dynein motor region"
FT /evidence="ECO:0000259|Pfam:PF12781"
FT DOMAIN 1731..1811
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 1854..1902
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 2063..2164
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT DOMAIN 2213..2261
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT REGION 235..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 471..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 912..1173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2032..2057
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 598..635
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 772..820
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 238..264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..396
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2034..2057
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CDJ69450.1"
SQ SEQUENCE 2265 AA; 238356 MW; D1BB840CF3A0F326 CRC64;
LYKQVKETLL PTPSRPFYIF NFRDLKSLFQ GLVAADADAI APRNALVRLW LHECTRTFGD
RLMCGEDREW LEREMKDLAS RKLFYSAAAA AAAAAAAAAR QQGAAAAAPH NLWGDWFTPG
QSRYTEAPAW QQLQKVLQLY REEAAAAAAA AAAGAAAGPA AAAAAAAAPL ASLVFFPDAV
SRIAAVSRHL KQQTRHLLLL GVAATGRSSS AKLAAAIRGL LLKEFVCHAI EDKDTSEAPW
GSPQQQPSSS SSSSSSSSSS SGGGGGDHAV AGAANPSQAS SSSSSSSSSS SSSSSSSALG
KFREDLKAAM LGAGLAAGKD TLLLLNESQI LDERILGDAD AVANTGEVLP RVEGLLDPEA
VETIVGDLSA SPAPRDSSSS SSSSSSSSSS SSSSSSSESA LRVFRENVLK RLRVCICLSP
VGGALRRRLR LFPGLTKAFA AVFFEVWGPT PLAAVAAHLF AAADLPQLQL PQQQQEQQQQ
QHGEAEELSA EAQQQRLQQQ QQQQLLQQQQ QQQHKSKLSQ LCVNIHLSAE AEAAAFLERE
GKRLLAERRE ALSRRLQLFS AGVQHIAAAA AQVKLLQQEL QQLGPFLREK HLKAEALLKQ
VEADKAVVDL EKKKVQEEEA IVSSHRAAAQ QLQHEAQQEF EEALPALEAA LSSLDSLDKR
DITEIKSFTK PPPLVLLTLE AICVLLAEKT DWEHARKVLS DTGFLNRLTT FDKEHIPATT
LKKLEKILQR PDFTPEVVGK QSVAAMSLCM WILAINKYAK VSKEVEPKRK KLAEADEALR
AAQSRCQLVE GKVNKMKKEL KEQIKEKEKL EEETKLCQIR LERASFLTQG LAKEAIRWKD
SLAAAAQHLA SVEGDSLLAA ASLIYLGPLA ESYRERLLLQ WQQQLQQQQL LHSSDFDIRQ
ILSNPVEINE WRMQQQQQRQ QQQQQQHFPH HQPAHTSTLI TPNTNTSSSS NSTSNSSSSS
SSSTCTHSSS STCTHSSSST RSSSSSNTAS SNSNTSSTRS SSSSSSSSNA TSSNSNTSST
RCSSSSSSSN TTSSNSNTSS TRSSSSSSSN ATSSNSNTSS TRCSSSSSSN TTSSNSNTSN
TRCSSSSSSN TTSSNSNTSS TRCSSSSSSN TTSSNSNTSS TRTRSSSSSS SNTTSSNSNT
SSTRSSSSSS SNTTSSTRST RSSSSSSSSS SRSAACVQGL PGDSCSTFGG VVVIGSISFG
RTPLAVDPQQ QAKRWFREKG KHEGLRAAKL QTPKLQNLLA ACARLGQPML IEDIEEEIPA
LFAPLLALPL KKKGGLGVAE KVSLVSFAVT REGLEEQLLM KILFLENPQV ERQSTQLQVQ
NAADLRQLQE LEETMLRLLS SSTSNILDDS ALTETLKEAS ATAAAVAARV TEAALVLQQL
SSSNLIFKPL AFRGSFMFFV VKELESLSCM YTSSLELFLD AFTQAIKSVP KTPQQQQQQQ
QQQQQQQQQQ QQQQQRQLGE AAAAAAAAAP APAAAAGAAE AAAAEAAAAA GTTEAAAEAA
EAAAAAAAAA ESKDRIQTLI QETTHAVYTQ TLMGLFEKHK LPFAFAVAAE IIKRELHPET
AEAAALLVGG CGLNAEAGRG EGLGEGLGEG LGEGLGEGLG EGLGEGLGEG LGEGLGPNPL
PELLQQQQWK QLLLLSRVLP SLKELPIHLV ANRDKWISYF SSANPQTLNP PLWQQQNPQT
LRVFETMMLL NIVRKDAVAA FALEVVSRVL GPSFCNLLPP SLEEALCCCS SSKPLLLLLS
PGADPAAALA ALAEQQNPKP QFECISLGRG QAPKASRVLA TALREGGWAL LQNCHLAKSW
MAELQQTVEG LGACLQEALG AIKSSKKESA AAAAAAAAAA AEAAAEADKG ESQWKSLKVS
LLVFHAVVQE RASYGPLGWN GSYCFSVSDL KASLELLRDA AAAAAAAAEQ LVLQRAQQLQ
QQLLGCLSLV RGPQTLDLQS AVVAAKEAAE DAAAARAAAR AAAAEADAAA APPSPIAAAD
AAKSDSRGKD RFKQIQDSLS VFFAQERSRY CSLLELINEG LLQLLLSLKG GPTGGPPGGP
PGGPPGGAPG GAPGGAPGGP PGGPRCYCLP LLFYPSGFAA ALLQQAARQQ QVAAELLQLE
FEFMGVVEPQ LLPLPQRQPK FGVYIHGLSL EGGSWDLLQQ QLSSKTNSLI CEPFPVMFVS
PRVSAAAAAA AAAAAAADAA AAANAAAAAD EDAAAAEDAA AADTEAAAAA AANEAAADNV
YSCPVYATAA RGGPENCVLS VPLPTAVPSS TCILRGTALL LEPRE
//
