ID   U7MN92_9CORY            Unreviewed;       517 AA.
AC   U7MN92;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN   ORFNames=HMPREF1290_01723 {ECO:0000313|EMBL:ERS71881.1};
OS   Corynebacterium sp. KPL1989.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC   Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=1203622 {ECO:0000313|EMBL:ERS71881.1, ECO:0000313|Proteomes:UP000017102};
RN   [1] {ECO:0000313|EMBL:ERS71881.1, ECO:0000313|Proteomes:UP000017102}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KPL1989 {ECO:0000313|EMBL:ERS71881.1,
RC   ECO:0000313|Proteomes:UP000017102};
RG   The Broad Institute Genomics Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Jacobson B., Goguen K.,
RA   Pagano E., Lemon K.P., Young S.K., Zeng Q., Gargeya S., Fitzgerald M.,
RA   Abouelleil A., Alvarado L., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA   Goldberg J., Gnerre S., Griggs A., Gujja S., Hansen M., Howarth C.,
RA   Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA   Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Corynebacterium sp. KPL1989.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ERS71881.1}.
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DR   EMBL; AXLR01000005; ERS71881.1; -; Genomic_DNA.
DR   RefSeq; WP_023019506.1; NZ_KI515717.1.
DR   AlphaFoldDB; U7MN92; -.
DR   PATRIC; fig|1203622.3.peg.1701; -.
DR   eggNOG; COG2304; Bacteria.
DR   HOGENOM; CLU_554038_0_0_11; -.
DR   Proteomes; UP000017102; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00198; vWFA; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017102};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          333..517
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          299..323
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        307..323
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   517 AA;  53509 MW;  096B58BF4ED11D5F CRC64;
     MGRHYTPEQK TQFSGGFIAS TIAILLAIIA VLAWLFLGNG SEDTGSNADS AEGESCIEGN
     LQLPVASGDA TLTQSLLASW NATKPVVRDH CVQAVIAEDI AKAAVYIDAD SPRLAQAVAA
     AGRTAAASGE HPKVAGQAAG IYDKHAATDA DVDLKLPANA VTYPGDSAAS AVVASALADG
     PESGAELLLR DENKSLADAD GPVAAVQAIS AQDAGSFRAL EGAYVEYAAA VLNQSDEIDE
     EQARAAQAFA DDLAAQYHGF EANPEVEGQV EAETDAKRLD ASPVWEAYLA RTALDFGNTG
     SKHQSNDDAA AQDHNKDDAK HAHDAADALT ATDTLFLLDT SDAMSSGFPG IAGPSRFQAS
     ADAIATLAPE LSAHGHSVAL WNYSSPLNPG VTQGFRRNID FSDGAETARS VQLLGTGGVP
     QTNEALLAAA HAVRDHSGIA QSESQPSRIV LITSGTADGY PDFPAKFREA LGAKAELSVV
     HVGDGETDPA LREVASHIQT VKNAAELEEK LRRVVGL
//