ID U7PHY5_SPOS1 Unreviewed; 868 AA.
AC U7PHY5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Transcription initiation factor IIB {ECO:0000256|ARBA:ARBA00013932};
DE AltName: Full=General transcription factor TFIIB {ECO:0000256|ARBA:ARBA00031706};
GN ORFNames=HMPREF1624_08414 {ECO:0000313|EMBL:ERS95203.1};
OS Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERS95203.1, ECO:0000313|Proteomes:UP000018087};
RN [1] {ECO:0000313|Proteomes:UP000018087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58251 / de Perez 2211183
RC {ECO:0000313|Proteomes:UP000018087};
RX PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA Goldberg J., Young S., Zeng Q., Birren B.W.;
RT "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT 58251).";
RL Genome Announc. 2:E0044614-E0044614(2014).
CC -!- SIMILARITY: Belongs to the TFIIB family.
CC {ECO:0000256|ARBA:ARBA00010857}.
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DR EMBL; KI440855; ERS95203.1; -; Genomic_DNA.
DR AlphaFoldDB; U7PHY5; -.
DR STRING; 1391915.U7PHY5; -.
DR eggNOG; KOG1597; Eukaryota.
DR HOGENOM; CLU_330425_0_0_1; -.
DR OrthoDB; 38673at2759; -.
DR Proteomes; UP000018087; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR GO; GO:0070897; P:transcription preinitiation complex assembly; IEA:InterPro.
DR CDD; cd20551; CYCLIN_TFIIB_rpt1; 1.
DR Gene3D; 1.10.472.170; -; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 1.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR000812; TFIIB.
DR InterPro; IPR023486; TFIIB_CS.
DR InterPro; IPR013150; TFIIB_cyclin.
DR InterPro; IPR013137; Znf_TFIIB.
DR PANTHER; PTHR11618:SF13; TRANSCRIPTION INITIATION FACTOR IIB; 1.
DR PANTHER; PTHR11618; TRANSCRIPTION INITIATION FACTOR IIB-RELATED; 1.
DR Pfam; PF08271; TF_Zn_Ribbon; 1.
DR Pfam; PF00382; TFIIB; 2.
DR PRINTS; PR00685; TIFACTORIIB.
DR SMART; SM00385; CYCLIN; 2.
DR SUPFAM; SSF47954; Cyclin-like; 2.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS00782; TFIIB; 1.
DR PROSITE; PS51134; ZF_TFIIB; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00469};
KW Reference proteome {ECO:0000313|Proteomes:UP000018087};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00469};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00469}.
FT TRANSMEM 106..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 543..576
FT /note="TFIIB-type"
FT /evidence="ECO:0000259|PROSITE:PS51134"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 76..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 205..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 316..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 458..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 589..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..489
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 868 AA; 93116 MW; 4AF7D63E872E25EF CRC64;
MPAFSTVPPA LSSQAVPVPS VSPASSLPTA APTSAPTSSF LESLSQPSLS PSSQISASSF
PPQPLHHVVV ALRGNVTTHP TPSSSTTPTL ISSDSKAHAG ASSNKWLPGV IVAAVVAVVA
AAALATWLTF RRRRRQRYEQ ARQHDPQLTP DQFRRRSHMS EAALMAEAER ERRHMIRKSL
LSRSSASLSY LGAAGEVAGE VAGDQGAQDD MEDGYRGVPL YQHQPVPRPP LQPQTQTQPQ
TQPSAGQWDL AHHDNLTPLD TLAPLATASL IPAPLNVSPP VSAAAAPPAR RDDDTEWTAA
LRRYHPHLTL DNVVEESESA LDQPLDQPLA GDVGVDSDRP ASPPVPPRSW LRPLSVVRPD
AAAGVVNLAP ADPLRQDSTA SQANGFTARQ VHADPRNALA HPSDAATTSP TSLYSVDFSQ
LALTILSDKT DAQTSDLTPA EATKSIVLVL DTLDAKKRLA SKKRKPRQTS TKVTRPATAK
SQPTRTQTKL VAATRKPLEE LHNKPSPSAT RAAAAAATTK MDAATATATA NAARDAYKEN
LDNIVMCPDC KEFPPNLVEE FSSGDMVCDS CGLVVGPRII DSRSEWRTFA NDDQGNDDPS
RVGESANSLA NDEGLRTQVD MRAANGKLAG KLNSINKKSQ SEKLNNDLQE GFRAISGLVD
MMQTSGIVGQ TAMHIYKLAY EHGQLKGKPR EAVIAGCIFI ACRQCGVPRT FREIYAITRV
TKKEIGRVFK SLESFLSKIQ EKNPQASAAQ GVKDYKASSS TTAEELCTRY CSLLGFRNTP
RMEKISKALA RKTTGIPDLA GRSPLSVAAA CIYFASQYLD DPRASKDIAS IAGVSDGTIK
TAYRFLYNTR TTLVEPDWHG DLDKLSSS
//
