ID U7PMU3_SPOS1 Unreviewed; 685 AA.
AC U7PMU3;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=OPT family small oligopeptide transporter {ECO:0000313|EMBL:ERS96877.1};
GN ORFNames=HMPREF1624_06203 {ECO:0000313|EMBL:ERS96877.1};
OS Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERS96877.1, ECO:0000313|Proteomes:UP000018087};
RN [1] {ECO:0000313|Proteomes:UP000018087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58251 / de Perez 2211183
RC {ECO:0000313|Proteomes:UP000018087};
RX PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA Goldberg J., Young S., Zeng Q., Birren B.W.;
RT "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT 58251).";
RL Genome Announc. 2:E0044614-E0044614(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the oligopeptide OPT transporter family.
CC {ECO:0000256|ARBA:ARBA00008807}.
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DR EMBL; KI440848; ERS96877.1; -; Genomic_DNA.
DR AlphaFoldDB; U7PMU3; -.
DR eggNOG; KOG2262; Eukaryota.
DR HOGENOM; CLU_004965_1_1_1; -.
DR OrthoDB; 2782392at2759; -.
DR Proteomes; UP000018087; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035673; F:oligopeptide transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR004648; Oligpept_transpt.
DR InterPro; IPR004813; OPT.
DR NCBIfam; TIGR00727; ISP4_OPT; 1.
DR NCBIfam; TIGR00728; OPT_sfam; 1.
DR PANTHER; PTHR22601; ISP4 LIKE PROTEIN; 1.
DR PANTHER; PTHR22601:SF12; OLIGOPEPTIDE TRANSPORTER 1; 1.
DR Pfam; PF03169; OPT; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Peptide transport {ECO:0000256|ARBA:ARBA00022856};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000018087};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 69..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 310..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 549..573
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 620..639
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 685 AA; 77570 MW; 103546F21FAAC414 CRC64;
MDILDVEDAS DEISTNSSRP LRQRVEETEL TPDEAFRWDV SGDQSPFPEV AACVPNTDDP
EMACSTFRAW TLTTIFVMLF AGVNQFFSLR YPSLTIGYVV AQLLVFPVGR AWENLPRWRL
PLGRLSFDIN PGRFTIKEHA LIVICVNISA SVAYASGSLV AIVSPVYWNR DYGAGFGFLY
LLTSQMLGFG LAGLARRWLV YPGALIWPTT LSSTVLFRAL HEPQEHAPVN GWTLSRYHFF
SWFSLFAFVL FWFPDYIWTS LGTFAFVTWI APHNQKVNTI FGMSSGLGLL PLSIDWTQIN
FAGFPLMTPF YITCNAFAVV VLFYLFLSPI LYYANVWNSA YLPLLSSTTY DNTGKTYNIT
RVVNENLDFV LSKYEEYSPM YISMSYSLTY ALSFAAVTSI VVYTYLYNGS EIYAKFKNAR
HGGEDIHKRL MNSYKEVPDW WYGVLTVSVL GLGILTIRYW ETGLPVWGFI VVCFGMGVLL
IVPEGILEGT TNQRIFLNII TELIAGYAWP GKPIANMMVK CYGYNSVKHG MDFAQDLKLG
QYMKIPPRVL FIGQIYASIL ATMTQVGVLR WMIGHIHGLC EPTNTNRFTC NGALVVYNAS
LIWGTIGPQR MFQSGQVYSG IMYFFLLGPV VTVLVYLVYR RYPKSWVRYI NVPIFFNAAG
QIPPANTTEG IWHHQGRTDS KFDTV
//
