ID U7PQR1_SPOS1 Unreviewed; 537 AA.
AC U7PQR1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=DUF1776-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1624_07044 {ECO:0000313|EMBL:ERS96835.1};
OS Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERS96835.1, ECO:0000313|Proteomes:UP000018087};
RN [1] {ECO:0000313|Proteomes:UP000018087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58251 / de Perez 2211183
RC {ECO:0000313|Proteomes:UP000018087};
RX PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA Goldberg J., Young S., Zeng Q., Birren B.W.;
RT "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT 58251).";
RL Genome Announc. 2:E0044614-E0044614(2014).
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DR EMBL; KI440849; ERS96835.1; -; Genomic_DNA.
DR AlphaFoldDB; U7PQR1; -.
DR STRING; 1391915.U7PQR1; -.
DR eggNOG; ENOG502QWSS; Eukaryota.
DR HOGENOM; CLU_022136_0_0_1; -.
DR OrthoDB; 1973638at2759; -.
DR Proteomes; UP000018087; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013952; DUF1776_fun.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43313:SF1; DEHYDROGENASES, SHORT CHAIN; 1.
DR PANTHER; PTHR43313; SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C; 1.
DR Pfam; PF08643; DUF1776; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018087};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 92..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 498..522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 498..512
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 537 AA; 58036 MW; 67FA5DE4D15E3F9C CRC64;
MSSDDNKPYM DMLTNVSSEV RRYSGEIAQY VDSNFDRAAD MLREQLASAP WIPEQVKVYL
PKPRSSTAME LTSKADMSFY ERVQDWLVRH KILATVAVLF AGTLSYRAVR RSISARKYRR
AKRAKNGARC EVVVIAASPA LPVTQSLALD MERRGYMVYI VCGSAEDEQA VRHMSRPDIK
PLSIDITDTA AASAALERFA LYLHAPHAAV PGAKRSHLQL TGIILIPSLN YQTSPIATIP
PANFADLFNT HLLHPILSIQ AFLPLLTART ALQPGDKPPS ILAAASGLSL AKIRQKASAS
ASQEKKEKTP TPPKVLVFTP SIISSVNPPF HAPESTVCSA LTAFTEVLAA ELRPLAIPVT
HIQLGTFDFT GFAPARSVTA HRSISGRMPL PAAETLSWSE PARHVYGRNF TAQSTSALGS
GRAIRGVRGT SMHDLHHAVF DVLDGSNTNA IVRVGLGADL YGFVGSFVPR GLVAWMMGVR
KVEDLSAWYQ APIPPTATSS VVSNNSDSPS PGRRSKRGAA NGVIAVGSEV GDSHIWQ
//
