ID U7PRM0_SPOS1 Unreviewed; 383 AA.
AC U7PRM0;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=SH3 domain-containing protein {ECO:0000259|PROSITE:PS50002};
GN ORFNames=HMPREF1624_05025 {ECO:0000313|EMBL:ERS98242.1};
OS Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERS98242.1, ECO:0000313|Proteomes:UP000018087};
RN [1] {ECO:0000313|Proteomes:UP000018087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58251 / de Perez 2211183
RC {ECO:0000313|Proteomes:UP000018087};
RX PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA Goldberg J., Young S., Zeng Q., Birren B.W.;
RT "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT 58251).";
RL Genome Announc. 2:E0044614-E0044614(2014).
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DR EMBL; KI440846; ERS98242.1; -; Genomic_DNA.
DR AlphaFoldDB; U7PRM0; -.
DR STRING; 1391915.U7PRM0; -.
DR eggNOG; KOG3601; Eukaryota.
DR HOGENOM; CLU_064525_0_0_1; -.
DR OrthoDB; 2994860at2759; -.
DR Proteomes; UP000018087; Unassembled WGS sequence.
DR CDD; cd00174; SH3; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR45929; JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018087};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 148..209
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 45..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 210..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..117
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..143
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..267
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..326
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..341
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 383 AA; 40191 MW; FE03124E1BE083D1 CRC64;
MGDTRQKAMD VNRSLRSIKT ELETLLEKGA ISDDDFNSIH DLLPQEWSLR GGPPPSAANK
QRQAPAIAAA AAALQPGQPG PPLPIRSSAQ PSAPSAASAS ATALAPAASS AAATPPTSGR
VQRDDRNDNE PDTKPDDNAD SADSDGRTAA GYATAKYKYE APSDGDLAFD RGDAIAVYSK
VNDDWWLGRN VRSGQVGIFP RQYVKPEAAL AELERNNQLP GPNDAPPPPV PRPAAGNSNS
TSNSRSASTA PPSYYDQFGN PPPQQQQYAG GDAKYGEPYG QQPYGQQPYG QQQPYGQQPY
GQPYGQPYGQ PYGQQHYGQQ QPYYGGGPSD QPPPPQQPQQ QPPEQGSGDK VGAAGKKIGG
KLGNAFVTGV GFAAGAELVG AIL
//
