ID   U7PS52_SPOS1            Unreviewed;       943 AA.
AC   U7PS52;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   03-MAY-2023, entry version 30.
DE   RecName: Full=C2H2-type domain-containing protein {ECO:0000259|PROSITE:PS50157};
GN   ORFNames=HMPREF1624_05186 {ECO:0000313|EMBL:ERS98402.1};
OS   Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS   disease fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX   NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERS98402.1, ECO:0000313|Proteomes:UP000018087};
RN   [1] {ECO:0000313|Proteomes:UP000018087}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58251 / de Perez 2211183
RC   {ECO:0000313|Proteomes:UP000018087};
RX   PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA   Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA   Goldberg J., Young S., Zeng Q., Birren B.W.;
RT   "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT   58251).";
RL   Genome Announc. 2:E0044614-E0044614(2014).
CC   -!- SIMILARITY: Belongs to the ARS2 family.
CC       {ECO:0000256|ARBA:ARBA00005407}.
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DR   EMBL; KI440846; ERS98402.1; -; Genomic_DNA.
DR   AlphaFoldDB; U7PS52; -.
DR   STRING; 1391915.U7PS52; -.
DR   eggNOG; KOG2295; Eukaryota.
DR   HOGENOM; CLU_014487_0_0_1; -.
DR   OrthoDB; 24436at2759; -.
DR   Proteomes; UP000018087; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR   InterPro; IPR025239; DUF4187.
DR   InterPro; IPR039727; SE/Ars2.
DR   InterPro; IPR007042; SERRATE/Ars2_C.
DR   InterPro; IPR021933; SERRATE/Ars2_N.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR13165; ARSENITE-RESISTANCE PROTEIN 2; 1.
DR   PANTHER; PTHR13165:SF0; SERRATE RNA EFFECTOR MOLECULE HOMOLOG; 1.
DR   Pfam; PF04959; ARS2; 1.
DR   Pfam; PF13821; DUF4187; 1.
DR   Pfam; PF12066; SERRATE_Ars2_N; 1.
DR   SMART; SM01173; DUF4187; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018087};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT   DOMAIN          705..735
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   REGION          1..120
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          144..172
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          498..526
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          595..645
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          827..862
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          906..943
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..76
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        105..119
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        602..625
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   943 AA;  103872 MW;  859D608B17305552 CRC64;
     MRSPPDRSWN DGRKDDRDPF YRGRSPGQPE RNRRPARSRS PTAVDRYEPR SRVRDEYGNG
     GGRDRDRDDR RRINSPPANI DRYVPGQPLH LATSSGGITT LTPPLHQQPP RPALTNPMPD
     PLTLPYQVGF SFFGEWWRTN EKIKEENEAQ RTGRRPERER QPRGPKEAQE EKAKIQAAYD
     TYKEEVQGKM ATAFVKQHKD EQWFIERYVP AVRDPLRQQL AEVRKSFYSQ WEQDLDTGLF
     DEFTLEGVSK SDTLAVAAAA EKEEGEAAAN DVLGVGDLVP AVAAADIRDE SLTAPTLLIK
     TIAPTVSRQN LENFCREHLG EGEGGYRWLS LSDPNPGKRY HRIGWIMLNP GPEGGFPVQD
     EDGNVDIENP ATVPVAERAL EAVNSKTVKD EVRGDFTCHV GVHNPPTNFR KKALWDLFSA
     PERIDRDLHL VQRLVAKFEA DVDSTFNGVF KVEEKVEELR HTGRLQPVHV SSTRPAAAKK
     RKVQKSRRVD MDVNLDFEVG GDDEMDDIED GEEDEEEEDG EELEDGVVVD DVDDEYVLGQ
     KKQLDLLIEY LRRVFNFCFF CVFESDSVHE LTRKCPGGHL RRPRSSLTPA ALEVARASAH
     GEPFPVKRHD PSSSADAEEG ELPDEGGRGG AGGDKGSGGK GRASLPKAEQ QLLRAFNWVK
     TFEEKISQVL DPGSTDLRKF GGKPLDDAMN DELANHVKQE DEHKYRCKLP ECTKLFKEEH
     FWRKHVEKRH SEWYEALKAD LELVNAYAAD PAHIAPSRTD ASSNGHFSAG AGQTPTGTPR
     GFNLHNYNLS AAGGLPSIPG FPGPGGNSGF NMFNPVAMQV PGSWQSPVGG SPGGPGPIRR
     GGGTRHNNNR TGPYDRRPMR WNPDSGITGG SPMYGGGGGR GGRNGGGGPG GFTVGGAVGL
     PGRWDGAGGG SAVGPREAIQ GRTIKSYDDL DQAGNGAGGE LNY
//