ID U7Q1P1_SPOS1 Unreviewed; 368 AA.
AC U7Q1P1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Plasma membrane iron permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1624_02119 {ECO:0000313|EMBL:ERT00885.1};
OS Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERT00885.1, ECO:0000313|Proteomes:UP000018087};
RN [1] {ECO:0000313|Proteomes:UP000018087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58251 / de Perez 2211183
RC {ECO:0000313|Proteomes:UP000018087};
RX PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA Goldberg J., Young S., Zeng Q., Birren B.W.;
RT "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT 58251).";
RL Genome Announc. 2:E0044614-E0044614(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC
CC 9.A.10.1) family. {ECO:0000256|ARBA:ARBA00008333}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI440843; ERT00885.1; -; Genomic_DNA.
DR AlphaFoldDB; U7Q1P1; -.
DR STRING; 1391915.U7Q1P1; -.
DR eggNOG; ENOG502QQWE; Eukaryota.
DR HOGENOM; CLU_046738_1_1_1; -.
DR OrthoDB; 1386471at2759; -.
DR Proteomes; UP000018087; Unassembled WGS sequence.
DR GO; GO:0033573; C:high-affinity iron permease complex; IEA:InterPro.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR004923; FTR1/Fip1/EfeU.
DR PANTHER; PTHR31632; IRON TRANSPORTER FTH1; 1.
DR PANTHER; PTHR31632:SF2; PLASMA MEMBRANE IRON PERMEASE; 1.
DR Pfam; PF03239; FTR1; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00022496};
KW Iron {ECO:0000256|ARBA:ARBA00022496};
KW Iron transport {ECO:0000256|ARBA:ARBA00022496};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018087};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022496}.
FT TRANSMEM 6..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 368 AA; 41206 MW; D06D4031F8091207 CRC64;
MGKNVFAVQV FFIVFRECLE AGIILSVLFS FLKQALGGPD QDPAIYKKMR RQVWLGAGTG
VLICFIIGGA FIGVFYGLGR NIWTGTEELW EGIFYLIATI IITAMGLALL RINKMREKWQ
VKIAQSLVTH HSIKDGTFMW IREWGRRNVM FILPFITTLR EGVEAVVFVG GVSLSLPATA
FPIPVITGII AALIIGLLLY RGGNHMTIQA FLIFSTSVLY LIAAGMFSRS IWFLQYYVFA
QRVGGDVAEA GSGPGSYDIS ATVWHVNYGN PEISNGWDVF NALLGWQNTG TYGTIISYNL
YWLFIIVSIV FLLYEERTGW LPFARPTLNF FSRVPGFKSW ARKRIAAHEV DADDVVNRVQ
AEHMVGQN
//
