ID U7Q2X9_SPOS1 Unreviewed; 566 AA.
AC U7Q2X9;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 13-SEP-2023, entry version 30.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1624_02298 {ECO:0000313|EMBL:ERT01061.1};
OS Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERT01061.1, ECO:0000313|Proteomes:UP000018087};
RN [1] {ECO:0000313|Proteomes:UP000018087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58251 / de Perez 2211183
RC {ECO:0000313|Proteomes:UP000018087};
RX PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA Goldberg J., Young S., Zeng Q., Birren B.W.;
RT "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT 58251).";
RL Genome Announc. 2:E0044614-E0044614(2014).
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000256|ARBA:ARBA00010992}.
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DR EMBL; KI440843; ERT01061.1; -; Genomic_DNA.
DR AlphaFoldDB; U7Q2X9; -.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_001265_11_5_1; -.
DR OrthoDB; 2665810at2759; -.
DR Proteomes; UP000018087; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR48022:SF5; ALPHA-GLUCOSIDES PERMEASE MPH2-RELATED; 1.
DR PANTHER; PTHR48022; PLASTIDIC GLUCOSE TRANSPORTER 4; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018087};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 83..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..498
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 566 AA; 61279 MW; 788E5C451E0279C2 CRC64;
MDGALSGPDS DTVNTLAASL MISTAVSPTV SASETLVDAS EHRSRTQYTS LYDDKKQWLK
AKTAVYVENL AARAHTLRTY YKAIIWSLLL MLPVILVGYA QNLAVSLLAQ PQFEERFSGD
EDDFGAAWML AVQMCSVGSS MLGGLLFSVR HILATSLMLF LGCTFINFWA PSMVVILVGT
LLQGLCSGGF GTLASTYISD VCTPTISNVL TGMISCCWIV GQLASYGVLW LMVDVEGAGA
YRIPMALQWV IPVPIAIACL AAPSSPWCHV RRGNTADALH ALERLTCSPD RRRSRFGIHP
TDPAVLRLAE IQAVVALETT QLTDKIEFRE CFRKSNRRRT EIAVMVNVGQ IVVGFAIASQ
LVNFMRLAGL KSDDSIKMAF FNAIILLLGS ICYFIFYTRL STRTMYLGGL GQAVLLFGWS
FLYGATVGPS TNTIVCDVSS AALRTKTLSL SRMANDMGSL MQSAAGPYML GHDKGNLQGL
TAFPAVGLIS IWIIWASVRL PEMKNIPQAV ADVLFARRIP ARRFQREANR LQVMDGQVVD
GQVDAVTGVG GPGVVVEVAN DAALVV
//
