ID U7Q3H8_SPOS1 Unreviewed; 1096 AA.
AC U7Q3H8;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Ribosomal protein S2 {ECO:0000313|EMBL:ERT01575.1};
GN ORFNames=HMPREF1624_02826 {ECO:0000313|EMBL:ERT01575.1};
OS Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERT01575.1, ECO:0000313|Proteomes:UP000018087};
RN [1] {ECO:0000313|Proteomes:UP000018087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58251 / de Perez 2211183
RC {ECO:0000313|Proteomes:UP000018087};
RX PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA Goldberg J., Young S., Zeng Q., Birren B.W.;
RT "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT 58251).";
RL Genome Announc. 2:E0044614-E0044614(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS2 family.
CC {ECO:0000256|ARBA:ARBA00006242}.
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DR EMBL; KI440843; ERT01575.1; -; Genomic_DNA.
DR AlphaFoldDB; U7Q3H8; -.
DR STRING; 1391915.U7Q3H8; -.
DR eggNOG; KOG0832; Eukaryota.
DR HOGENOM; CLU_009026_0_0_1; -.
DR OrthoDB; 1328303at2759; -.
DR Proteomes; UP000018087; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015935; C:small ribosomal subunit; IEA:InterPro.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR CDD; cd17781; CBS_pair_MUG70_1; 1.
DR CDD; cd17782; CBS_pair_MUG70_2; 1.
DR CDD; cd01425; RPS2; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR HAMAP; MF_00291_B; Ribosomal_S2_B; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR001865; Ribosomal_uS2.
DR InterPro; IPR005706; Ribosomal_uS2_bac/mit/plastid.
DR InterPro; IPR018130; Ribosomal_uS2_CS.
DR InterPro; IPR023591; Ribosomal_uS2_flav_dom_sf.
DR NCBIfam; TIGR01011; rpsB_bact; 1.
DR PANTHER; PTHR13780; AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR13780:SF125; MEIOTICALLY UP-REGULATED GENE 70 PROTEIN; 1.
DR Pfam; PF00571; CBS; 4.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF00318; Ribosomal_S2; 1.
DR PRINTS; PR00395; RIBOSOMALS2.
DR SMART; SM00116; CBS; 4.
DR SMART; SM00666; PB1; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 2.
DR SUPFAM; SSF52313; Ribosomal protein S2; 1.
DR PROSITE; PS51371; CBS; 4.
DR PROSITE; PS00962; RIBOSOMAL_S2_1; 1.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000018087};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980,
KW ECO:0000313|EMBL:ERT01575.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 108..166
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 175..231
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 278..335
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 344..401
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT REGION 1..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 599..675
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 750..781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..89
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..778
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1096 AA; 117401 MW; 9F66F6F4A3D8CB62 CRC64;
MSGNTVRGTP NRGQARGAIP FNNSPAANSS IPRPVLDNHS HIGSDGGAAA GGGGGGAASS
VSASRQKQSK RDEAIRRKLE SDLNKKKPNA PGRARHSRKA PPGTVLALKP SPALQIKPAT
TVAEAAQLMA AKREDCVLVT DDDDRIAGIF TAKDLAFRVV GAGLKANTAT IAEIMTKNPL
CARTDTSATD ALDLMVRKGF RHLPVMDENQ DISGILDITK CFYDAMEKLE RAYSSSRKLY
DALEGVQSEL GASQPQQIIQ YVEALRSKMS GPTLESVLNG LPPTTVSVRT SVKEAAQLMK
DNHTTAVLVQ DQGAITGIFT SKDVVLRVIA PGLDPANCSV VRVMTPHPDF APMDMSIQAA
LRKMHDGHYL NLPVMNDSGE IVGMVDVLKL TYATLEQINT MSSGDSEGPA WNKFWLSLDH
ETESMVSGDG SHHHTHMTSS RMMSPELSRD AHGNILHGRV DSVAPGDSAS HVGVESPPHS
AVAPITPELP PSEVPFPFKF KAPSGRVHRL QVIAAQGVAV FVENVASKLG AEADTIGGVP
AVADGKVTGA GFAISYLDDE GDSVSITADQ DLVEAVLLAR HGHLEKVDLF VHDPSKPPVA
AAATPALPTP ASSDRATSGV RSRRGIHRSS GDDEDEDDDE DEDSDDSAYV RKQKTKARRA
RRNNNRSKGS IGSAAESVGA ASKAFGEFAA NSFGAGTDEQ LIQGVPNDLL LPGAIVTLSV
VILGRGALVT PPAPISSQLS QICRRAFLST DSTTTSIPSQ TTPPTTSTQP SRPNTAPQPY
GTKRVPLALR PEMTSHLAAK FVAKGKAKRK TAGLGSSVER LYVPDELIRN PPYPKDVTLE
LLMASQTHLG HNTSLWNPAN SRYIHGIRTG IHIISLEQTA LYLRRAARVV EEVAYHGGII
LFVGTRKGQA DIVVRAAELA GGCHVFDRWQ GGTITNRDQM LFRSKQRIVD EQDRDISDEG
FRSHLLRRRP LIPDLVVVLN PMENFVLLRE CAGATVPTIG VIDTDADPGR VSYPIPANDD
SLRSAALIAG VLGRAGELGQ KRRLRDAREG VVAWENAEEI NRFMDKRNRA NEALESGEKR
KVKWSSRTAL SGGNIF
//
