ID U7UAV8_9FIRM Unreviewed; 521 AA.
AC U7UAV8;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Putative heme utilization radical SAM enzyme HutW {ECO:0000313|EMBL:ERT56441.1};
GN ORFNames=HMPREF1250_1499 {ECO:0000313|EMBL:ERT56441.1};
OS Megasphaera vaginalis.
OC Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC Megasphaera.
OX NCBI_TaxID=1111454 {ECO:0000313|EMBL:ERT56441.1, ECO:0000313|Proteomes:UP000017090};
RN [1] {ECO:0000313|EMBL:ERT56441.1, ECO:0000313|Proteomes:UP000017090}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BV3C16-1 {ECO:0000313|EMBL:ERT56441.1,
RC ECO:0000313|Proteomes:UP000017090};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERT56441.1}.
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DR EMBL; AWXA01000062; ERT56441.1; -; Genomic_DNA.
DR RefSeq; WP_023054604.1; NZ_AWXA01000062.1.
DR AlphaFoldDB; U7UAV8; -.
DR STRING; 1111454.HMPREF1250_1499; -.
DR PATRIC; fig|1111454.3.peg.2140; -.
DR eggNOG; COG0635; Bacteria.
DR OrthoDB; 9808022at2; -.
DR Proteomes; UP000017090; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR034505; Coproporphyrinogen-III_oxidase.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR026332; HutW.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; TIGR04107; rSAM_HutW; 1.
DR PANTHER; PTHR13932; COPROPORPHYRINIGEN III OXIDASE; 1.
DR PANTHER; PTHR13932:SF9; COPROPORPHYRINOGEN III OXIDASE-RELATED; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDF00311; heme_degradation_proteins_(Hut; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000017090};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 63..299
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 521 AA; 58939 MW; 149338BC59FCCEBF CRC64;
MLLQELYDRQ SPAERAFLFG CEGVDALTAA FPHKRVVHAG LEGTVVAPAE AQQIWKGLLA
QPPQSQPTQS AYIHIPFCKT KCLYCGFFQN GENQQAENRY IDCLLEDIRR DAAQPRLRDS
LIHSVFIGGG TPTSLSVPNV KRLLQAIRAY LPLANDYELT LEGRIHDLVP EKMEVWLANG
VNRISLGVQS FHTAVRRNVG RLDDTETVLK RLAALKAYNQ CVVVIDLIYG LPGQSMAVWQ
EDLRILSAYD IDGADLYQLN VFEDSDLQRR IADGTLPPAA TTAEQAEMFA FARDYLKKRN
YRRVNICHWS NTNRERSLYN SLTRQGVPMF PFGSGAGGNL DGYSTMLHRA LEPYEMAVDQ
GEKPFMALLK QSAQQPLVNA LLKQLEQRYI DLRQLVSYQE RLKELKWLFD LWQERGLLRD
NGVCYELTEA GEFWQVNIAQ STLECMEYLV TGKKQLQIQG VAAQDTGKQG RIDAKAEAIV
KVMKEMKENG GSRMAAMQEM AEAMRSMTAE EMQAVMKRMR P
//
