ID U7UKM3_9FIRM Unreviewed; 458 AA.
AC U7UKM3;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Xanthine permease {ECO:0000313|EMBL:ERT59977.1};
GN Name=pbuX {ECO:0000313|EMBL:ERT59977.1};
GN ORFNames=HMPREF1250_0888 {ECO:0000313|EMBL:ERT59977.1};
OS Megasphaera vaginalis.
OC Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC Megasphaera.
OX NCBI_TaxID=1111454 {ECO:0000313|EMBL:ERT59977.1, ECO:0000313|Proteomes:UP000017090};
RN [1] {ECO:0000313|EMBL:ERT59977.1, ECO:0000313|Proteomes:UP000017090}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BV3C16-1 {ECO:0000313|EMBL:ERT59977.1,
RC ECO:0000313|Proteomes:UP000017090};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERT59977.1}.
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DR EMBL; AWXA01000028; ERT59977.1; -; Genomic_DNA.
DR RefSeq; WP_023053552.1; NZ_AWXA01000028.1.
DR AlphaFoldDB; U7UKM3; -.
DR STRING; 1111454.HMPREF1250_0888; -.
DR PATRIC; fig|1111454.3.peg.1082; -.
DR eggNOG; COG2233; Bacteria.
DR OrthoDB; 9805749at2; -.
DR Proteomes; UP000017090; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR017588; UacT-like.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR NCBIfam; NF037981; NCS2_1; 1.
DR NCBIfam; TIGR03173; pbuX; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000017090};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 28..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 458 AA; 47243 MW; 4F8BEAE8411B2457 CRC64;
MECDVEKETV VTGDELLYGI ESRPPVRMAL ILALQHILAA FAGIIAVPLV VCSALGMSVE
QTSLMVSATI FVSGITTVLQ SRGFGPVGSR VSGMMGTDFT FVNPSISVGA QFGVAGIVAA
TMTGSLVEIV LSRFIRPLMK FFPPLITGTV VSLIGITLLP VSIDWAAGGV GAKDYGSLEN
LAVSFSIMLL TLLLNHYGKG ISSTAAVFIG MVAGYILCIP LGMVDLTPVA TAEWLAVPNI
FRYGFVFDLA STLAFVPAYL VSTIGTVGIM IAIGESSREK LSSDRVASGV LCDGVGSLLA
GLFGAGPNTA FSQNVGLIAL TKVASRRVMV LAGAILTILG IFPKLSALIA VMPSAVLGGA
GVIMFGLVAA QGIKTLASIH LGDRELLIIS VSFALGIGVT VKPEILRNLP GMLQMIFSSG
ISTGTLTALL LNIVLAAPEK MSEKRLDDAA GTGEAGCQ
//
