ID   U9TDJ2_RHIID            Unreviewed;      1151 AA.
AC   U9TDJ2;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=VPS10 domain-containing protein {ECO:0000259|SMART:SM00602};
GN   ORFNames=GLOINDRAFT_260133 {ECO:0000313|EMBL:ESA01436.1};
OS   Rhizophagus irregularis (strain DAOM 181602 / DAOM 197198 / MUCL 43194)
OS   (Arbuscular mycorrhizal fungus) (Glomus intraradices).
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Glomeromycotina;
OC   Glomeromycetes; Glomerales; Glomeraceae; Rhizophagus.
OX   NCBI_TaxID=747089 {ECO:0000313|EMBL:ESA01436.1};
RN   [1] {ECO:0000313|EMBL:ESA01436.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=DAOM 197198 {ECO:0000313|EMBL:ESA01436.1};
RG   DOE Joint Genome Institute;
RA   Tisserant E., Malbreil M., Kuo A., Kohler A., Symeonidi A., Balestrini R.,
RA   Charron P., Duensing N., Frei-dit-Frey N., Gianinazzi-Pearson V.,
RA   Gilbert B., Handa Y., Hijri M., Kaul R., Kawaguchi M., Krajinski F.,
RA   Lammers P., Lapierre D., Masclaux F.G., Murat C., Morin E., Ndikumana S.,
RA   Pagni M., Petitpierre D., Requena N., Rosikiewicz P., Riley R., Saito K.,
RA   San Clemente H., Shapiro H., van Tuinen D., Becard G., Bonfante P.,
RA   Paszkowski U., Shachar-Hill Y., Young J.P., Sanders I.R., Henrissat B.,
RA   Rensing S.A., Grigoriev I.V., Corradi N., Roux C., Martin F.;
RT   "The genome of an arbuscular mycorrhizal fungus provides insights into the
RT   evolution of the oldest plant symbiosis.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KI296461; ESA01436.1; -; Genomic_DNA.
DR   AlphaFoldDB; U9TDJ2; -.
DR   eggNOG; KOG3511; Eukaryota.
DR   HOGENOM; CLU_000700_0_0_1; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.10.70.80; -; 2.
DR   Gene3D; 3.30.60.270; -; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR031777; Sortilin_C.
DR   InterPro; IPR031778; Sortilin_N.
DR   InterPro; IPR006581; VPS10.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR12106; SORTILIN RELATED; 1.
DR   PANTHER; PTHR12106:SF27; VPS10 HOMOLOG 1-RELATED; 1.
DR   Pfam; PF15902; Sortilin-Vps10; 2.
DR   Pfam; PF15901; Sortilin_C; 2.
DR   SMART; SM00602; VPS10; 2.
DR   SUPFAM; SSF110296; Oligoxyloglucan reducing end-specific cellobiohydrolase; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          1..568
FT                   /note="VPS10"
FT                   /evidence="ECO:0000259|SMART:SM00602"
FT   DOMAIN          590..1151
FT                   /note="VPS10"
FT                   /evidence="ECO:0000259|SMART:SM00602"
SQ   SEQUENCE   1151 AA;  131276 MW;  B1C0B94BA7979174 CRC64;
     MWFTTDSGNT FDKTELKNEP NKLNLKMLDF HPKEYDWLLY MAGTTCPGCH SITYFSSDNG
     KSWKEIETWA DKCIFGKDTE FSETENDAVF CSSYKDKNSK ISQDILGGRT SEANPLQLVK
     MRTDGGSKKV LFNDVVNYFV FNEFMAVATE ERGELLLHIS EDGSKFSNAT FPPDINVNQQ
     AYTILPSTTG SIFLDVYKSL RLGSEYGSLF KSNSDGTDFN RILDNTNRNV FGNVDFEKVQ
     GLDGIILANQ VVNIDELNDY VKKRIITKIS YDDGSHWKRL RFNGGDSSCQ DCHLNLHGRT
     DIRGPGSIFS APSAVGLLIG VGNFGPHLLP YNECNTFMSR DGGRIWKEIR RGPSLYEFGD
     QGTIIVVVDN EAPTDHVRYS WDYGENWEKY TFTTSTPVRV SLLTTNSKST SMKFLLLGYT
     VQTSTHEASP VVVTLDFSQL EKRKCDKDDY ELWNPMDENS DDHTCLLGEE IKFWRRKANA
     ECHIGESIPK PPERKTCKCT KHDFECAHGY WRNETGQCEL MGPDPDRPAN CKDKYLGHSG
     YVKMKKSKCE GGENFDKKIE KPCDSGNIVI SKTKVFDQRI AEYFYFNESN TILARSMDNI
     VWRSTDEGYT WTSVSKEKIY GLIQNPHFNK YAYLITLGDR HLYTSDSGAT FNEFKVPTKP
     NLLQIPILSF HLDKPEYLIY IGSIDCEDEW SQTCHTQASY TWNNGKDWKS LDTYVRVCQW
     ARNKKFKVHQ DLIICESYLN KEGSQKTFFN NPLKLVSSDN FFKNKNTAPI ENIVGFTIYE
     EFMIVAELLP SGQSLRLLVS LDAKNFAEAQ FPPNMLMTQN AYTVLESATY SITLHVTTSA
     TYKYGNILKS NGNGTFYSFS LGYANRDDKG FVDFEKMQGI QGIALANIVG NVDEVNMGNN
     KKLKSKITTN DGATWKLLNR PEFDSDNNKY KCDGPLDKCS LHLHSYTERR NPRDSFSSSS
     ATGLMMGVGN VGEYLTPYLE GDTFLTRDAG ATWIEVKKGA YMYEFGNQGG IIVLVDDEQA
     TDHILYSLNE GLSWQEYKFI KVGEQPIRVF DIDTMPGGLS SKFILRGLNP SRGGEEVVVH
     LDFSHIFTRT CNLEKDFEKW TPKHQDNECL FGHKISYLRK IRENECYIED KLRYKKERGE
     NCDCTDHDFE W
//