ID U9W3J3_NEUCR Unreviewed; 484 AA.
AC U9W3J3;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 28-JUN-2023, entry version 31.
DE RecName: Full=DNA repair protein rad9 {ECO:0000256|PIRNR:PIRNR009303};
GN ORFNames=NCU00470 {ECO:0000313|EMBL:ESA43392.1};
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110 {ECO:0000313|EMBL:ESA43392.1, ECO:0000313|Proteomes:UP000001805};
RN [1] {ECO:0000313|EMBL:ESA43392.1, ECO:0000313|Proteomes:UP000001805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC {ECO:0000313|Proteomes:UP000001805};
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA Lander E.S., Nusbaum C., Birren B.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
CC -!- FUNCTION: Acts in DNA repair and mutagenesis. Involved in promoting
CC resistance to ionizing radiation and UV light, as well as regulating
CC cell cycle progression after irradiation.
CC {ECO:0000256|PIRNR:PIRNR009303}.
CC -!- SIMILARITY: Belongs to the rad9 family. {ECO:0000256|ARBA:ARBA00008494,
CC ECO:0000256|PIRNR:PIRNR009303}.
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DR EMBL; CM002238; ESA43392.1; -; Genomic_DNA.
DR RefSeq; XP_011393856.1; XM_011395554.1.
DR AlphaFoldDB; U9W3J3; -.
DR STRING; 367110.U9W3J3; -.
DR EnsemblFungi; ESA43392; ESA43392; NCU00470.
DR GeneID; 3872936; -.
DR KEGG; ncr:NCU00470; -.
DR VEuPathDB; FungiDB:NCU00470; -.
DR InParanoid; U9W3J3; -.
DR OrthoDB; 1111055at2759; -.
DR Proteomes; UP000001805; Chromosome 3, Linkage Group III.
DR GO; GO:0030896; C:checkpoint clamp complex; IBA:GO_Central.
DR GO; GO:0071479; P:cellular response to ionizing radiation; IBA:GO_Central.
DR GO; GO:0006281; P:DNA repair; IBA:GO_Central.
DR GO; GO:0000076; P:DNA replication checkpoint signaling; IBA:GO_Central.
DR GO; GO:0031573; P:mitotic intra-S DNA damage checkpoint signaling; IBA:GO_Central.
DR Gene3D; 3.70.10.10; -; 1.
DR InterPro; IPR046938; DNA_clamp_sf.
DR InterPro; IPR026584; Rad9.
DR InterPro; IPR007268; Rad9/Ddc1.
DR PANTHER; PTHR15237:SF0; CELL CYCLE CHECKPOINT CONTROL PROTEIN; 1.
DR PANTHER; PTHR15237; DNA REPAIR PROTEIN RAD9; 1.
DR Pfam; PF04139; Rad9; 1.
DR PIRSF; PIRSF009303; Cell_cycle_RAD9; 1.
DR SUPFAM; SSF55979; DNA clamp; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|PIRNR:PIRNR009303};
KW Reference proteome {ECO:0000313|Proteomes:UP000001805}.
FT REGION 296..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..369
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 484 AA; 54531 MW; 8B94964F9BF1F881 CRC64;
MVILNFTLSE EGVSVFHDAL ACMYKFSDDV CLEARRDKLT LTTLNISKSA YVCFTFAANR
FFSRYHFEGN AQYRDRFFCQ LYIRSLLSIF RSRQGGDSAR DKDASIERCD VAIDDGPGKK
SRLIARISCR NGITASHSLP FESKPPTHAK FEKDEAGNRW SISSSTLRQL MDHFGPGIEL
LDINTDDDDH VVNFTCFTDK VQKRGPHGNE AVLKKPLHTN ISVEMAEFNE VEVQDKLHII
ISVKDFRAIL QHAQIISGEL ATYYSEPGRP MKLSYSADGI LCEFILMTVG EQDAITQKHK
NTRARASKTP KPGSGPGPGP ASKPDGSVAN NEAKDVPKPA QKPPQQKTPP QPRQTQFEIR
PPPIPPRSPV AARTDRSDSP LFVEQGDEDR QWDPVDREDE EEMDNARVEW NATGEPVLLR
HFPLVARKKM ANIHSRTRRP CELAVYWQDR LCPVMSQTDL LGDSSQPSSF LRHVSCCLLC
LFFC
//
