ID V2K7H5_9BURK Unreviewed; 1374 AA.
AC V2K7H5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=ATP-dependent helicase {ECO:0000313|EMBL:ESJ22368.1};
GN ORFNames=B551_0207960 {ECO:0000313|EMBL:ESJ22368.1};
OS Cupriavidus sp. HPC(L).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=1217418 {ECO:0000313|EMBL:ESJ22368.1, ECO:0000313|Proteomes:UP000053474};
RN [1] {ECO:0000313|EMBL:ESJ22368.1, ECO:0000313|Proteomes:UP000053474}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HPC(L) {ECO:0000313|Proteomes:UP000053474};
RA Purohit H.J., Agarwal L.;
RT "Cupriavidus a Desert isolate.";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESJ22368.1}.
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DR EMBL; AMPR02000101; ESJ22368.1; -; Genomic_DNA.
DR RefSeq; WP_023263805.1; NZ_AMPR02000101.1.
DR OrthoDB; 9805617at2; -.
DR Proteomes; UP000053474; Unassembled WGS sequence.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:ESJ22368.1};
KW Helicase {ECO:0000313|EMBL:ESJ22368.1};
KW Hydrolase {ECO:0000313|EMBL:ESJ22368.1};
KW Nucleotide-binding {ECO:0000313|EMBL:ESJ22368.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053474}.
FT DOMAIN 90..287
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 343..514
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 124..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 305..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1297..1328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..62
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 131..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..339
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1374 AA; 155227 MW; DC3CF79C19150C7D CRC64;
MSEQRPVPPA APRRRPSRPQ SARQSQGPSK SRSQGSSQGP TEDQAERKPE RKPERRFEGR
PARRAVLANP LPPITFPEAL PVSARRDEIA RAIEQHQVVI VSGETGSGKT TQLPKICLSI
GRGPARADAA GGEGKGEEHG EETGEDQGKD KDGQPRRRGG LIGHTQPRRI AATSTAKRIA
QELGSPVGEH VGYQVRFNDT MSPGASIKLM TDGILLAETQ TDPLLRAYDT IIIDEAHERS
LNIDFLLGYL KEILPRRPDL KVIITSATID AQRFAEHFGS GGKPAPVIEV SGRLYPVEVR
YRPIADEGGA NQRGDKGDKG DKGDKGARAG DGPAKAAQAR ERDLYDGIVD AVDELSRLGP
GDVLVFLPGE REIREAAEAL RKHHPPHTEI LPLFARLSVQ EQERVFKPSN ARRIVLATNV
AETSLTVPGI RYVVDTGLAR VKRYSYRNKV EQLQIEPISQ AAANQRAGRC GRVADGVCIR
LYDEADFAAR PRFTDPEILR SSLAAVILRM KALRLGAIES FPFIEPPLGR AIADGYQLLQ
ELGAVDEANA LTPLGKQLAR LPLDPRVARM ILAARDQHCL REVLIIASAL SVQDPRDRPQ
EAQEAADQAH RKFMDERSEF LGWVKLWKWF EDAVAHKKSN RQLQDQCRAN FLSHLRLREW
RDVHSQLLTT VAEQGWKLND SEPTYEQVHK ALLTGLLGNI GQKLDEADGR GREYLGARGI
KFHLWPGSLV ARKMGRWLVA AELVETSRLF ARTLARIEPD WLEQVGRHLL KVSWSDPHWE
KKAGQVLAME RATLYGLTVY QHRRVHYGPM NPREARELFI RRALVEGEFD TRLPFYAHNQ
RLVREIENLE HKARRQDVLV DDELIYAFYD RHIPADIHQQ TQFEQWYQKE SAGDRKLLYL
NREELMRHEA AGITTDLFPK TLNVAGVDMG LSYHFEPGSH RDGVTLTVPL YALNQVRPER
ADWLVPGMIK EKVHLLLKSL PQKLRRHCVP LPDYAAGFVE RRPFGEGELI DVLIADVREQ
TGTMIRRADF KLETLPAHHF MNFKVVDEHG RQLDMGRNLA QLRAELGGQA QQSFQSLVAR
EAPVAEAAQY EGLTGWTFGE LPELLEIRKG NRTLFGYPAL VDRDTHCDVE VFDDPQEAER
LHHAGLRRLF ALQLREQVKF VQKNIPGLSQ MAMQYMTLGT QDMLRDQIVT LALERACMQA
PLPRNEAEFA ARKEEGRGRL GLLAQEIARL AGTILAEYAA LPRKLLQAKP FAAAHADMQA
QLSQLMGKHF LAETPYDRLV HFPRYLKGIA MRIDKLKGDP SRDTQRQQEM APLLQQWQRA
DKQRRQARGG EDARLEEFRW MLEELRIALF AQELRTPVPM SVKRLQKVWE SMQR
//
