ID V2PXU4_9BACT Unreviewed; 490 AA.
AC V2PXU4;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=RNA polymerase sigma-54 factor {ECO:0000313|EMBL:ESJ97447.1};
GN Name=rpoN {ECO:0000313|EMBL:USF23129.1};
GN ORFNames=N508_000184 {ECO:0000313|EMBL:USF23129.1}, N508_01369
GN {ECO:0000313|EMBL:ESJ97447.1};
OS Mucispirillum schaedleri ASF457.
OC Bacteria; Deferribacterota; Deferribacteres; Deferribacterales;
OC Mucispirillaceae; Mucispirillum.
OX NCBI_TaxID=1379858 {ECO:0000313|EMBL:ESJ97447.1};
RN [1] {ECO:0000313|EMBL:ESJ97447.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ASF457 {ECO:0000313|EMBL:ESJ97447.1};
RX PubMed=24723722;
RA Wannemuehler M.J., Overstreet A.M., Ward D.V., Phillips G.J.;
RT "Draft genome sequences of the altered schaedler flora, a defined bacterial
RT community from gnotobiotic mice.";
RL Genome Announc. 2:e00287-e00214(2014).
RN [2] {ECO:0000313|EMBL:USF23129.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ASF457 {ECO:0000313|EMBL:USF23129.1};
RA Proctor A.L., Phillips G.J., Wannemuehler M.J.;
RL Submitted (MAY-2022) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:USF23129.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ASF457 {ECO:0000313|EMBL:USF23129.1};
RA Proctor A., Parvinroo S., Richie T., Jia X., Lee S.T.M., Karp P.D.,
RA Paley S., Kostic A.D., Pierre J.F., Wannemuehler M.J., Phillips G.J.;
RT "Resources to Facilitate Use of the Altered Schaedler Flora (ASF) Mouse
RT Model to Study Microbiome Function.";
RL Submitted (JUN-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the sigma-54 factor family.
CC {ECO:0000256|ARBA:ARBA00008798}.
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DR EMBL; AYGZ01000018; ESJ97447.1; -; Genomic_DNA.
DR EMBL; CP097562; USF23129.1; -; Genomic_DNA.
DR RefSeq; WP_023276199.1; NZ_FTRD01000001.1.
DR AlphaFoldDB; V2PXU4; -.
DR STRING; 1379858.N508_01369; -.
DR GeneID; 78586923; -.
DR PATRIC; fig|1379858.3.peg.1370; -.
DR eggNOG; COG1508; Bacteria.
DR HOGENOM; CLU_020569_1_1_0; -.
DR OrthoDB; 9814402at2; -.
DR Proteomes; UP000017429; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001216; F:DNA-binding transcription activator activity; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.10.1330; RNA polymerase sigma-54 factor, core-binding domain; 1.
DR InterPro; IPR000394; RNA_pol_sigma_54.
DR InterPro; IPR007046; RNA_pol_sigma_54_core-bd.
DR InterPro; IPR007634; RNA_pol_sigma_54_DNA-bd.
DR InterPro; IPR038709; RpoN_core-bd_sf.
DR NCBIfam; TIGR02395; rpoN_sigma; 1.
DR PANTHER; PTHR32248; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR PANTHER; PTHR32248:SF4; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR Pfam; PF00309; Sigma54_AID; 1.
DR Pfam; PF04963; Sigma54_CBD; 1.
DR Pfam; PF04552; Sigma54_DBD; 1.
DR PIRSF; PIRSF000774; RpoN; 1.
DR PRINTS; PR00045; SIGMA54FCT.
DR PROSITE; PS00717; SIGMA54_1; 1.
DR PROSITE; PS00718; SIGMA54_2; 1.
DR PROSITE; PS50044; SIGMA54_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000017429};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 125..315
FT /note="RNA polymerase sigma factor 54 core-binding"
FT /evidence="ECO:0000259|Pfam:PF04963"
FT DOMAIN 330..487
FT /note="RNA polymerase sigma factor 54 DNA-binding"
FT /evidence="ECO:0000259|Pfam:PF04552"
FT REGION 58..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 490 AA; 56049 MW; FE10DA777413CA6C CRC64;
MNNLNQNLDI KNTLQTTVFI TPQMKQSLAI LQMPIVELEQ ELSNILEENP VLEAVEDDGS
DDLYDFDNNE SNNLSEDIED TQDKDKNLDN LVEKVTGDDW EEYIGYEKLD DISYKSTNDE
NSFDIEQVIG AKESLYEHLM YQLNINIIDK EERLIGEYII GNLSEDGYFR IDIKDACSEL
SVEESLFEKV LDIIKTFTPS GIASSSLQEC VIVQIKDMNC DAVYVDLAEE LLAGYSAELA
AFKYDDILKG MSIERDTFDY LLQLIKKTDP RPGLNFSGSD TKFITPDVFI VPNEESFDII
VNEKGIPNIR LNNYYIKMLQ GSNLDSEAKT YIKDKVKNAV WVIESLQKRQ KAIYKVVKSI
VGFQGEFLQY GISMLKPLKL KDIAESTGLH ESTVSRVTSG KYAMTKHGLI ELKSFFSKSL
ESQDGDMSIG VIKQKIKELI DEEDKEVCLS DQRIVELMEE KGIKIARRTV AKYRDEMNIP
TMSQRRRLRR
//
