ID V2QC05_9BACT Unreviewed; 204 AA.
AC V2QC05;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=3'-5' exonuclease {ECO:0000256|ARBA:ARBA00040531};
DE AltName: Full=Werner Syndrome-like exonuclease {ECO:0000256|ARBA:ARBA00042761};
GN Name=rnd {ECO:0000313|EMBL:USF24158.1};
GN ORFNames=N508_001237 {ECO:0000313|EMBL:USF24158.1}, N508_00698
GN {ECO:0000313|EMBL:ESJ98486.1};
OS Mucispirillum schaedleri ASF457.
OC Bacteria; Deferribacterota; Deferribacteres; Deferribacterales;
OC Mucispirillaceae; Mucispirillum.
OX NCBI_TaxID=1379858 {ECO:0000313|EMBL:ESJ98486.1};
RN [1] {ECO:0000313|EMBL:ESJ98486.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ASF457 {ECO:0000313|EMBL:ESJ98486.1};
RX PubMed=24723722;
RA Wannemuehler M.J., Overstreet A.M., Ward D.V., Phillips G.J.;
RT "Draft genome sequences of the altered schaedler flora, a defined bacterial
RT community from gnotobiotic mice.";
RL Genome Announc. 2:e00287-e00214(2014).
RN [2] {ECO:0000313|EMBL:USF24158.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ASF457 {ECO:0000313|EMBL:USF24158.1};
RA Proctor A.L., Phillips G.J., Wannemuehler M.J.;
RL Submitted (MAY-2022) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:USF24158.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ASF457 {ECO:0000313|EMBL:USF24158.1};
RA Proctor A., Parvinroo S., Richie T., Jia X., Lee S.T.M., Karp P.D.,
RA Paley S., Kostic A.D., Pierre J.F., Wannemuehler M.J., Phillips G.J.;
RT "Resources to Facilitate Use of the Altered Schaedler Flora (ASF) Mouse
RT Model to Study Microbiome Function.";
RL Submitted (JUN-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AYGZ01000012; ESJ98486.1; -; Genomic_DNA.
DR EMBL; CP097562; USF24158.1; -; Genomic_DNA.
DR RefSeq; WP_023275527.1; NZ_FTRD01000012.1.
DR AlphaFoldDB; V2QC05; -.
DR STRING; 1379858.N508_00698; -.
DR GeneID; 78587972; -.
DR eggNOG; COG0349; Bacteria.
DR HOGENOM; CLU_049674_2_1_0; -.
DR OrthoDB; 9793333at2; -.
DR Proteomes; UP000017429; Chromosome.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR CDD; cd06141; WRN_exo; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR13620; 3-5 EXONUCLEASE; 1.
DR PANTHER; PTHR13620:SF109; WERNER SYNDROME-LIKE EXONUCLEASE; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:USF24158.1};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000017429}.
FT DOMAIN 10..180
FT /note="3'-5' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00474"
SQ SEQUENCE 204 AA; 22935 MW; 48C9D8BA41AC45D3 CRC64;
MEPISFKGSI AVVDNLSKAE AALDKLFAAK YIGFDTESRP AFFKGQKFPV SIIQLATNEE
AFIFQLKYVH FSGRLVELLS DENIIKVGVG VQDDIRRLNE LCKFKQGGFY DLSSAAKKKG
LVQSGARALT ARYLGRKLVK SSQKTNWALS KLSPRQLEYA ATDAWICLQL LEHVKHDTTD
YRKLAALERE AGNLSDNEEY HIDE
//
