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Database: UniProt
Entry: V2TQS8_9GAMM
LinkDB: V2TQS8_9GAMM
Original site: V2TQS8_9GAMM 
ID   V2TQS8_9GAMM            Unreviewed;       363 AA.
AC   V2TQS8;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   08-MAY-2019, entry version 28.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=P256_00858 {ECO:0000313|EMBL:ESK40406.1};
OS   Acinetobacter nectaris CIP 110549.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Moraxellaceae; Acinetobacter.
OX   NCBI_TaxID=1392540 {ECO:0000313|EMBL:ESK40406.1, ECO:0000313|Proteomes:UP000023785};
RN   [1] {ECO:0000313|EMBL:ESK40406.1, ECO:0000313|Proteomes:UP000023785}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIP 110549 {ECO:0000313|EMBL:ESK40406.1,
RC   ECO:0000313|Proteomes:UP000023785};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Cerqueira G., Feldgarden M., Courvalin P., Grillot-Courvalin C.,
RA   Clermont D., Rocha E., Yoon E.-J., Nemec A., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Berlin A.M.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Gnerre S., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A., Larimer J.,
RA   McCowan C., Murphy C., Pearson M., Poon T.W., Priest M., Roberts A.,
RA   Saif S., Shea T., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Acinetobacter nectaris CIP 110549.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ESK40406.1}.
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DR   EMBL; AYER01000003; ESK40406.1; -; Genomic_DNA.
DR   RefSeq; WP_023272440.1; NZ_KI530712.1.
DR   STRING; 1392540.P256_00858; -.
DR   EnsemblBacteria; ESK40406; ESK40406; P256_00858.
DR   PATRIC; fig|1392540.3.peg.830; -.
DR   OrthoDB; 853329at2; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000023785; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000023785};
KW   Reference proteome {ECO:0000313|Proteomes:UP000023785};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       52    348       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   363 AA;  39957 MW;  CF6B4C007CDEF666 CRC64;
     MNTEQQNSTT SNDIDDVNIS SMQPLITPAQ LKAELPLSGK AHETVLKGRE QVRKILDGED
     KRIFVVIGPC SIHDPKAAHE YADRLKALSE KVKDTLYIIM RVYFEKPRTT VGWKGLINDP
     NMDDSFDIEK GLRIGRQLLL DLNEKGLPCA TEALDPNSPQ YLQDLISWSA IGARTTESQT
     HREMSSGLSS PVGFKNGTDG SFTVAINAMQ AVKHGHNFLG LNNDGQVSII RTRGNQYGHV
     VLRGGNGKPN YDATSVAAAE DALTKAKVAH HIMIDGSHAN SNKDPYLQPL VLKNVTEQIQ
     NGNRSIIGLM VESHLKGGRQ DIPSNLCDLE YGKSVTDGCI DWDTTEKVLL EMHQALKDVL
     PKR
//
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