ID   V2V2Y1_9GAMM            Unreviewed;       266 AA.
AC   V2V2Y1;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=Ribonuclease Z {ECO:0000313|EMBL:ESK55260.1};
GN   ORFNames=F990_02049 {ECO:0000313|EMBL:ESK55260.1};
OS   Acinetobacter tjernbergiae DSM 14971 = CIP 107465.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Acinetobacter.
OX   NCBI_TaxID=1120928 {ECO:0000313|EMBL:ESK55260.1, ECO:0000313|Proteomes:UP000017404};
RN   [1] {ECO:0000313|EMBL:ESK55260.1, ECO:0000313|Proteomes:UP000017404}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIP 107465 {ECO:0000313|EMBL:ESK55260.1,
RC   ECO:0000313|Proteomes:UP000017404};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Cerqueira G., Feldgarden M., Courvalin P., Grillot-Courvalin C.,
RA   Clermont D., Rocha E., Yoon E.-J., Nemec A., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Berlin A.M.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Gnerre S., Griggs A., Gujja S.,
RA   Hansen M., Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C.,
RA   Murphy C., Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T.,
RA   Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Acinetobacter tjernbergiae CIP107465.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ESK55260.1}.
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DR   EMBL; AYEV01000019; ESK55260.1; -; Genomic_DNA.
DR   AlphaFoldDB; V2V2Y1; -.
DR   STRING; 202955.GCA_000759995_00395; -.
DR   PATRIC; fig|1120928.5.peg.2078; -.
DR   eggNOG; COG1234; Bacteria.
DR   Proteomes; UP000017404; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016891; F:RNA endonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   CDD; cd07717; RNaseZ_ZiPD-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR013471; RNase_Z/BN.
DR   PANTHER; PTHR46018; ZINC PHOSPHODIESTERASE ELAC PROTEIN 1; 1.
DR   PANTHER; PTHR46018:SF2; ZINC PHOSPHODIESTERASE ELAC PROTEIN 1; 1.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   tRNA processing {ECO:0000256|ARBA:ARBA00022694};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          33..146
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|Pfam:PF12706"
SQ   SEQUENCE   266 AA;  29348 MW;  020F7C6DCE8DDFAF CRC64;
     MLHFTFLGTS SGVPTLTRNV SGLAIRNSNN KDWILVDAGE GTQHRIQQAK LSLQSLVAIC
     ITHVHGDHCY GLVGLLASAG MNARTAPLTI IAPKQIQQWI EITAQLTDLH LPYPLKFIDV
     NEATQIQQLT DELSIQAHPL SHRVPSFAFS IIAQYTQKKL DTQALIQLGV PKGKVWGYLQ
     QGLDLQFNEQ TLKAVDFIQI QTQRVHAIVG GDNDRPELLA QACQDAQLLI HESTYTQTIL
     DKVGSGPMHS SAKMVAEFKQ SHPDSF
//