ID V2VTQ0_9GAMM Unreviewed; 193 AA.
AC V2VTQ0;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Putative NAD(P)H nitroreductase {ECO:0000256|PIRNR:PIRNR000232};
DE EC=1.-.-.- {ECO:0000256|PIRNR:PIRNR000232};
GN ORFNames=P255_01635 {ECO:0000313|EMBL:ESK51129.1};
OS Acinetobacter brisouii CIP 110357.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=1341683 {ECO:0000313|EMBL:ESK51129.1, ECO:0000313|Proteomes:UP000018418};
RN [1] {ECO:0000313|EMBL:ESK51129.1, ECO:0000313|Proteomes:UP000018418}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIP 110357 {ECO:0000313|EMBL:ESK51129.1,
RC ECO:0000313|Proteomes:UP000018418};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Cerqueira G., Feldgarden M., Courvalin P., Grillot-Courvalin C.,
RA Clermont D., Rocha E., Yoon E.-J., Nemec A., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Berlin A.M.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Gnerre S., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Acinetobacter brisouii CIP 110357.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|PIRSR:PIRSR000232-1};
CC Note=Binds 1 FMN per subunit. {ECO:0000256|PIRSR:PIRSR000232-1};
CC -!- SIMILARITY: Belongs to the nitroreductase family.
CC {ECO:0000256|ARBA:ARBA00007118, ECO:0000256|PIRNR:PIRNR000232}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESK51129.1}.
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DR EMBL; AYEU01000006; ESK51129.1; -; Genomic_DNA.
DR RefSeq; WP_004900551.1; NZ_KI530762.1.
DR AlphaFoldDB; V2VTQ0; -.
DR STRING; 396323.VH98_02780; -.
DR PATRIC; fig|1341683.3.peg.1620; -.
DR HOGENOM; CLU_070764_5_0_6; -.
DR OrthoDB; 9804207at2; -.
DR Proteomes; UP000018418; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-UniRule.
DR CDD; cd02135; YdjA-like; 1.
DR Gene3D; 3.40.109.10; NADH Oxidase; 1.
DR InterPro; IPR029479; Nitroreductase.
DR InterPro; IPR000415; Nitroreductase-like.
DR InterPro; IPR026021; YdjA-like.
DR PANTHER; PTHR43821; NAD(P)H NITROREDUCTASE YDJA-RELATED; 1.
DR PANTHER; PTHR43821:SF1; NAD(P)H NITROREDUCTASE YDJA-RELATED; 1.
DR Pfam; PF00881; Nitroreductase; 1.
DR PIRSF; PIRSF000232; YdjA; 1.
DR SUPFAM; SSF55469; FMN-dependent nitroreductase-like; 1.
PE 3: Inferred from homology;
KW Flavoprotein {ECO:0000256|PIRNR:PIRNR000232};
KW FMN {ECO:0000256|PIRNR:PIRNR000232, ECO:0000256|PIRSR:PIRSR000232-1};
KW NAD {ECO:0000256|PIRNR:PIRNR000232}; NADP {ECO:0000256|PIRNR:PIRNR000232};
KW Oxidoreductase {ECO:0000256|PIRNR:PIRNR000232};
KW Reference proteome {ECO:0000313|Proteomes:UP000018418}.
FT DOMAIN 13..169
FT /note="Nitroreductase"
FT /evidence="ECO:0000259|Pfam:PF00881"
FT BINDING 16..18
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /ligand_note="ligand shared between dimeric partners"
FT /note="in other chain"
FT /evidence="ECO:0000256|PIRSR:PIRSR000232-1"
FT BINDING 45
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /ligand_note="ligand shared between dimeric partners"
FT /evidence="ECO:0000256|PIRSR:PIRSR000232-1"
FT BINDING 139..141
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /ligand_note="ligand shared between dimeric partners"
FT /note="in other chain"
FT /evidence="ECO:0000256|PIRSR:PIRSR000232-1"
SQ SEQUENCE 193 AA; 21233 MW; 515C4F8383F2AAC3 CRC64;
MANTTVKVVH DNIQHRQSVG HLVEPAPNKQ QLDLAFTAAL TAPDHHRLKP TRFVVIENNQ
RAAFGELLAQ AMQQYFPETD PVQIERVKNH PFRAPILVLA LTQIVEHPKV PAYEQILSSG
AAVENFLLSL QSQGFATMWR TGAVVESVAL KAALGLQAHD LISGIIYVGT ADKQLPARAT
VDLAAYVRYW SAP
//
