ID V2X4P6_MONRO Unreviewed; 543 AA.
AC V2X4P6;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 22-FEB-2023, entry version 34.
DE RecName: Full=Acetyl-CoA hydrolase {ECO:0000256|ARBA:ARBA00017958};
DE EC=3.1.2.1 {ECO:0000256|ARBA:ARBA00011920};
DE AltName: Full=Acetyl-CoA deacylase {ECO:0000256|ARBA:ARBA00029672};
GN ORFNames=Moror_11650 {ECO:0000313|EMBL:ESK87430.1};
OS Moniliophthora roreri (strain MCA 2997) (Cocoa frosty pod rot fungus)
OS (Crinipellis roreri).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Marasmiaceae; Moniliophthora.
OX NCBI_TaxID=1381753 {ECO:0000313|EMBL:ESK87430.1, ECO:0000313|Proteomes:UP000017559};
RN [1] {ECO:0000313|EMBL:ESK87430.1, ECO:0000313|Proteomes:UP000017559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCA 2997 {ECO:0000313|EMBL:ESK87430.1,
RC ECO:0000313|Proteomes:UP000017559};
RX PubMed=24571091; DOI=10.1186/1471-2164-15-164;
RA Meinhardt L.W., Costa G.G.L., Thomazella D.P.T., Teixeira P.J.P.L.,
RA Carazzolle M.F., Schuster S.C., Carlson J.E., Guiltinan M.J.,
RA Mieczkowski P., Farmer A., Ramaraj T., Crozier J., Davis R.E., Shao J.,
RA Melnick R.L., Pereira G.A.G., Bailey B.A.;
RT "Genome and secretome analysis of the hemibiotrophic fungal pathogen,
RT Moniliophthora roreri, which causes frosty pod rot disease of cacao:
RT mechanisms of the biotrophic and necrotrophic phases.";
RL BMC Genomics 15:164-164(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O = acetate + CoA + H(+); Xref=Rhea:RHEA:20289,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30089,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=3.1.2.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001831};
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESK87430.1}.
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DR EMBL; AWSO01000785; ESK87430.1; -; Genomic_DNA.
DR RefSeq; XP_007853275.1; XM_007855084.1.
DR AlphaFoldDB; V2X4P6; -.
DR STRING; 1381753.V2X4P6; -.
DR KEGG; mrr:Moror_11650; -.
DR HOGENOM; CLU_019748_3_0_1; -.
DR OrthoDB; 100792at2759; -.
DR Proteomes; UP000017559; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0003986; F:acetyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:ESK87430.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000017559}.
FT DOMAIN 25..250
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 351..501
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
SQ SEQUENCE 543 AA; 60455 MW; 21F5B92FEA0EA6BB CRC64;
MKATRTLRNA SIAGPSAALR ERVRRPQYFK KLAKPSNLAP LFKNDDYIGW SGFTGVGYPK
GTPTAIADHI EANNLQANPE TKKRFNLFVG ASVGPEVEDR WARMDMIARR YPHQVGKDIA
KGINTGKIEF ADKHLSMFPQ DLTYGYYSLQ KKHGDPKKPL DWAIVEATAI TEEGFIVPGA
SIGATPEIVQ SAEKIIIEVN TRIPNLEGLH DINHSFIPPH RQPYLITHPS DRIGTTAIPI
DTERVVAVVE SNQPDNTGEN APENEESRAI ARHLIEFLQS EVEAGRLPKN LLPLQSGIGN
VANSIIGGLA GGPFEKVQVW TEVLQDTFIE FFDSGKLDFA TATSIRFSPG GFDHFYKNWE
RYKDRLLLRS QQVANSPELI RRLGVIAMNT PLEVDIYGHA NSTNALGSRM LNGLGGSADF
LRNAKLSIMH TPSSRPTKTD PTGISCIVPF SSHIDQTEHD LDVVVTEQGL ADLRGLSPRE
RAPIIIKQCA HPDYRDMLLE YYDRALHECM KRGAGHEPHM LRNAFKLHTN FLEKGTMKIT
SWD
//
