ID V2XBL7_MONRO Unreviewed; 1072 AA.
AC V2XBL7;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Atp-dependent helicase nam7 {ECO:0000313|EMBL:ESK90181.1};
GN ORFNames=Moror_7746 {ECO:0000313|EMBL:ESK90181.1};
OS Moniliophthora roreri (strain MCA 2997) (Cocoa frosty pod rot fungus)
OS (Crinipellis roreri).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Marasmiaceae; Moniliophthora.
OX NCBI_TaxID=1381753 {ECO:0000313|EMBL:ESK90181.1, ECO:0000313|Proteomes:UP000017559};
RN [1] {ECO:0000313|EMBL:ESK90181.1, ECO:0000313|Proteomes:UP000017559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCA 2997 {ECO:0000313|EMBL:ESK90181.1,
RC ECO:0000313|Proteomes:UP000017559};
RX PubMed=24571091; DOI=10.1186/1471-2164-15-164;
RA Meinhardt L.W., Costa G.G.L., Thomazella D.P.T., Teixeira P.J.P.L.,
RA Carazzolle M.F., Schuster S.C., Carlson J.E., Guiltinan M.J.,
RA Mieczkowski P., Farmer A., Ramaraj T., Crozier J., Davis R.E., Shao J.,
RA Melnick R.L., Pereira G.A.G., Bailey B.A.;
RT "Genome and secretome analysis of the hemibiotrophic fungal pathogen,
RT Moniliophthora roreri, which causes frosty pod rot disease of cacao:
RT mechanisms of the biotrophic and necrotrophic phases.";
RL BMC Genomics 15:164-164(2014).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the DNA2/NAM7 helicase family.
CC {ECO:0000256|ARBA:ARBA00007913}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESK90181.1}.
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DR EMBL; AWSO01000466; ESK90181.1; -; Genomic_DNA.
DR RefSeq; XP_007850502.1; XM_007852311.1.
DR AlphaFoldDB; V2XBL7; -.
DR STRING; 1381753.V2XBL7; -.
DR KEGG; mrr:Moror_7746; -.
DR HOGENOM; CLU_001666_4_0_1; -.
DR OrthoDB; 170190at2759; -.
DR Proteomes; UP000017559; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR CDD; cd21407; 1B_UPF1-like; 1.
DR CDD; cd18039; DEXXQc_UPF1; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR CDD; cd21400; ZBD_UPF1-like; 1.
DR Gene3D; 2.40.30.230; -; 1.
DR Gene3D; 6.10.140.1240; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR040812; UPF1_1B_dom.
DR InterPro; IPR018999; UPF1_CH/ZBD.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF364; REGULATOR OF NONSENSE TRANSCRIPTS 1; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF18141; UPF1_1B_dom; 1.
DR Pfam; PF09416; UPF1_Zn_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51997; UPF1_CH_RICH; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ESK90181.1};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ESK90181.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU01341}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000017559};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU01341};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU01341}.
FT DOMAIN 87..242
FT /note="Upf1"
FT /evidence="ECO:0000259|PROSITE:PS51997"
FT REGION 31..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 95..127
FT /note="C3H"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01341"
FT REGION 109..137
FT /note="CC/SHH/C"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01341"
FT REGION 155..185
FT /note="C4"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01341"
FT REGION 990..1072
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 990..1047
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1072 AA; 118974 MW; 914EF99DE2F15387 CRC64;
MDSFDNFQYD TGSSYGGMSI VDDTSSVYTA TTQDNGSSVD LSSLSISDDS PNGQAQSGIG
QPNGQVHRHE LDEDFDAVLD DLKDEGQVDL PPHACSYCGI HSPASVVKCL ICNKWFCNSR
GNTSASHIVN HLVRAKHKEV ILHADSPLGE TAPECYNCGS KNVFMLGFIP AKSDTVVVLL
CRQPCAAISK EISWNSALWA PLIDDRSFLS WLVKPPSENE QLRSRQISFD QINRLEDLWR
DNANATLEDL EKPGVDDEPL PILLRYEDAY QYQNIFGPLV KIEADYDKKL KESQTQTDIT
VRWDIGLNQK RVAWFCLPKL ESGEVRLAVG DELRLRYLGE LHKPWEGVGH VIKIPNNVSD
EVALELRRTE GVPSECTQNF AADFVWKSTS FDRMQLAMKT FAVDEKSVSG YIYHKLLGHD
LEPNVLRTQM PKRWSAPGLP ELNHSQMFAV KSVLQKPISL IQGPPGTGKT VTSATIVYHL
AKMNPDQVLV CAPSNVAVDQ LTEKIHATGL KVVRLTAKSR EALDSSVSFL TLHQQVANST
HHVELQKLIQ LKNEQGELSS NDERKYKTLI RQCEKEILTA AEVICCTCVG AGDPRLSKLK
FRTVLIDEAT QAAEPECMIP LVLGCKQVVL VGDHQQLGPV IMNKKAARAG LTQSLFERLV
LLGNRPIRLQ VQYRMHPCLS EYPSNMFYEG SLQNGVTAPE RLRKNVDFPW PVPDTPMFFY
QNLGQEEISS SGTSFLNRTE ASNVEKIVTK FFKSGVVPNQ IGVVTPYEGQ RSYIVNYMQF
NGSLKKDLYK EVEVASVDAF QGREKDYIIL SCVRSNEHQG IGFLNDPRRL NVALTRAKYG
VVILGNPKVL SKHPLWHDLL THYKSKECLV EGPLSNLQIS MIQFSKPKRP LSKAMDQFRR
HETNARDYLG GASAGMGRSG TPSRFDPSFY RTHDALGYIP SDVQSLRSQA TYSSGLPMFT
ANGPFSAQVP RGTGAKRSAY GSYASSIISQ DAGPSTDNSS VVGSAVGSER PNLSYNQSDR
LRRRPSFGSS SVAGTSDLGS LSQYDYKSQG EEVDMDDMKS QYTGTQSGVT VF
//
