ID V2Y5B5_9FIRM Unreviewed; 622 AA.
AC V2Y5B5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=HNH endonuclease domain protein {ECO:0000313|EMBL:ESL04118.1};
GN ORFNames=GCWU0000282_000465 {ECO:0000313|EMBL:ESL04118.1};
OS Catonella morbi ATCC 51271.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Catonella.
OX NCBI_TaxID=592026 {ECO:0000313|EMBL:ESL04118.1, ECO:0000313|Proteomes:UP000018227};
RN [1] {ECO:0000313|EMBL:ESL04118.1, ECO:0000313|Proteomes:UP000018227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51271 {ECO:0000313|EMBL:ESL04118.1,
RC ECO:0000313|Proteomes:UP000018227};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESL04118.1}.
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DR EMBL; ACIL03000005; ESL04118.1; -; Genomic_DNA.
DR AlphaFoldDB; V2Y5B5; -.
DR STRING; 592026.GCWU0000282_000465; -.
DR eggNOG; COG1403; Bacteria.
DR eggNOG; COG3344; Bacteria.
DR HOGENOM; CLU_013584_14_3_9; -.
DR Proteomes; UP000018227; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00085; HNHc; 1.
DR CDD; cd01651; RT_G2_intron; 1.
DR Gene3D; 1.10.30.50; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR030931; Group_II_RT_mat.
DR InterPro; IPR002711; HNH.
DR InterPro; IPR003615; HNH_nuc.
DR InterPro; IPR000477; RT_dom.
DR NCBIfam; TIGR04416; group_II_RT_mat; 1.
DR PANTHER; PTHR34047:SF2; NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR34047; NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF01844; HNH; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SMART; SM00507; HNHc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:ESL04118.1};
KW Hydrolase {ECO:0000313|EMBL:ESL04118.1};
KW Nuclease {ECO:0000313|EMBL:ESL04118.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018227}.
FT DOMAIN 88..356
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 622 AA; 72023 MW; 190E970EF3644B5C CRC64;
MVTVSTSKQT LKQSKIRYTE YYDLQKVLDD LYEDSSKNKI FSNLMELITS RENIKLAYRS
IKGNKGSHTA GVDGRTIKHL SRLNEEKYIS LIQKQFHWYK PRPVKRVEMR KSNGKIRPLG
IPTIVDRIVQ QCILQILEPI CEAKFHDSSY GFRPNRSTDH AIAECARLMQ IQHLHYVVDI
DIQGFFDNVY HAKLIRQLWN LGIQDKKLLC IIKEMLKADI VMPDKEVITP TKGIPQGGIL
SPLLSNVVLN ELDWWVSSQW LTMPTHYPYK QRTNSQGTEI KSHTYRALRT SNLKEIYIVR
YADDFKIFCR NYYDAKRTYQ AVTKWLQDRL KLNVSEEKSK ITNLKQRYSE FLGFKLKVKP
KGKKFVVQSH ISDKALKNAK EDISKCVADI KRPANEKEQY KAIAKYNATV SGLHNYYQIA
TNVSLDFTKI AFHIKKQMNN RLDIKTSGTL SKGFIKEKYG KSKQLRFLNG HPLIPVGYIR
TKDAKHKKKV VNKYTVKGRA FIHKNLQIDV DTLVWLMKHP VLDKSIEFAD NRISLFAAQY
GRCGVTGVKL IPNDIHCHHK IPLEQGGTDS YSNLILVTEA VHILIHATKE DTIQKYIKEL
GLTVKQIEKC NKLRKMAELP LI
//
