ID V2Y7S7_9FIRM Unreviewed; 868 AA.
AC V2Y7S7;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Putative translation elongation factor G {ECO:0000313|EMBL:ESL03736.1};
GN ORFNames=GCWU0000282_000901 {ECO:0000313|EMBL:ESL03736.1};
OS Catonella morbi ATCC 51271.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Catonella.
OX NCBI_TaxID=592026 {ECO:0000313|EMBL:ESL03736.1, ECO:0000313|Proteomes:UP000018227};
RN [1] {ECO:0000313|EMBL:ESL03736.1, ECO:0000313|Proteomes:UP000018227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51271 {ECO:0000313|EMBL:ESL03736.1,
RC ECO:0000313|Proteomes:UP000018227};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Abolishes the inhibitory effect of tetracyclin on protein
CC synthesis by a non-covalent modification of the ribosomes.
CC {ECO:0000256|ARBA:ARBA00003987}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESL03736.1}.
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DR EMBL; ACIL03000007; ESL03736.1; -; Genomic_DNA.
DR RefSeq; WP_023353785.1; NZ_KI535367.1.
DR AlphaFoldDB; V2Y7S7; -.
DR STRING; 592026.GCWU0000282_000901; -.
DR eggNOG; COG0480; Bacteria.
DR HOGENOM; CLU_002794_5_0_9; -.
DR OrthoDB; 9801472at2; -.
DR Proteomes; UP000018227; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR CDD; cd10912; PIN_YacP-like; 1.
DR CDD; cd03711; Tet_C; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR035650; Tet_C.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR InterPro; IPR010298; YacP-like.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43261:SF1; RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43261; TRANSLATION ELONGATION FACTOR G-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF05991; NYN_YacP; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR PRINTS; PR01037; TCRTETOQM.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Elongation factor {ECO:0000313|EMBL:ESL03736.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000018227}.
FT DOMAIN 1..230
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 868 AA; 97077 MW; FB7FBE76ABC9AFCA CRC64;
MEHIVFGILA QVDAGKTTLS EGLLFSAGAL KKAGRVDKKD AFLDNYELER ERGITIFSKQ
AEFSAYGKSF TLLDTPGHVD FSVEMERVLS VLDVAILVIS ASAGVQSQVS VIWKLLKHYS
IPTYIFVNKM DQPGASKENI LKELKEKLDS NIIGYAQSAS TEYNTFLEEV SLCDETVLES
YMAEGEIKLS EIQELIQNRK FFPVFFGSAL KNEGVEEFLE NFAKLTVCPV YKTEFAARVF
KIARDTAGNR LTYMKLMGGS LSVREMIGDE KVTGIRMYSG EKFENRDTVK AGEVCAITGL
KNTKAGEGLG SLAGTRMGSV LRQVMSYRVE LPENEPVHVF LPKIKEISEE IPELSVKYSE
DKKEINISLM GEVQTEVLKH LIKERYNIDI NFGEGHILYK ETIADTVYGE GHFEPLRHYA
EVELRLEPAE RGSGLSFATE VSEDELAINY QKLILSHLEE KEYKGVLTGS PITDMKITLV
AGRAHLKHTE GGDFRQATYR AVRQGLMQAR PVLLEPVYDF KLEVPEEAIG RAMTDMGKMN
GNFASPENKS GKAVLTGKIP VSEVKDYALE LRAYTKGEGL LSLSPSDYEV CHNAEEVIER
FQYYPEADIE NTADSVFCSH GAGFVVPWNE VINYMHLPYF GKAAEEESEE EAFLRYANRA
ESQVGSDRGE VFLGTDEIDS ILNSAVSSNK KREAETARNR WKNRGKSEPE TVANTVNSKI
RSSIGKNDYL LVDGYNIVFA WEELKELAEI NIDSARDKLI EKLANYQGYK GCKLILVFDA
YKVRGGKENI IKQGNMWIVY TKEAETADQY IAKTSLELTK EGLVRVATSD ALVQMIIFGS
GAARISAREL EAEVKYVEGL ISEKLDKM
//
