ID V2YU83_MONRO Unreviewed; 879 AA.
AC V2YU83;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Reverse transcriptase-rnase h-integrase {ECO:0008006|Google:ProtNLM};
GN ORFNames=Moror_4032 {ECO:0000313|EMBL:ESK95209.1};
OS Moniliophthora roreri (strain MCA 2997) (Cocoa frosty pod rot fungus)
OS (Crinipellis roreri).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Marasmiaceae; Moniliophthora.
OX NCBI_TaxID=1381753 {ECO:0000313|EMBL:ESK95209.1, ECO:0000313|Proteomes:UP000017559};
RN [1] {ECO:0000313|EMBL:ESK95209.1, ECO:0000313|Proteomes:UP000017559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCA 2997 {ECO:0000313|EMBL:ESK95209.1,
RC ECO:0000313|Proteomes:UP000017559};
RX PubMed=24571091; DOI=10.1186/1471-2164-15-164;
RA Meinhardt L.W., Costa G.G.L., Thomazella D.P.T., Teixeira P.J.P.L.,
RA Carazzolle M.F., Schuster S.C., Carlson J.E., Guiltinan M.J.,
RA Mieczkowski P., Farmer A., Ramaraj T., Crozier J., Davis R.E., Shao J.,
RA Melnick R.L., Pereira G.A.G., Bailey B.A.;
RT "Genome and secretome analysis of the hemibiotrophic fungal pathogen,
RT Moniliophthora roreri, which causes frosty pod rot disease of cacao:
RT mechanisms of the biotrophic and necrotrophic phases.";
RL BMC Genomics 15:164-164(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESK95209.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AWSO01000102; ESK95209.1; -; Genomic_DNA.
DR RefSeq; XP_007845485.1; XM_007847294.1.
DR AlphaFoldDB; V2YU83; -.
DR KEGG; mrr:Moror_4032; -.
DR HOGENOM; CLU_000384_38_1_1; -.
DR OrthoDB; 1614028at2759; -.
DR Proteomes; UP000017559; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 2.40.50.40; -; 1.
DR Gene3D; 3.10.20.370; -; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF00385; Chromo; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF00665; rve; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SMART; SM00298; CHROMO; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50013; CHROMO_2; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000017559};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT DOMAIN 1..85
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT DOMAIN 457..617
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT DOMAIN 756..815
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT REGION 844..879
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 853..879
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 879 AA; 101280 MW; 0D09D00F7397C96E CRC64;
MVMFFGLSNS PATFQSFMDD IFSDYLEEGW VVIYMDDILI FSSDQKTHQK RTIQILERLR
LHDLFLKPEK CKFDVTEIDF LGMIIRPGYI GMDPVKLAGI RDWKPPTTVR GVRSFLGFGN
FYRKFIRRFS EIAKPLNELT KKDKKFEWTT KCQLAFDTLK EKFLSEPVLI MPDTEKPFLI
ECDASKWATG AVLRQQGTDG EWHPCGYISH SLTPTERNYE IYDREMFSIV RALMSWRHYL
MGGKHPITIL SDHKNLMFFK DAQKLNRRQA RWSLFLSQFD LQLVHTPGTK MTQSDALSRR
PDHVDDNEND NNNVVMLPDK FFLRAMDVKL HNDLIENLKG ETLYDDAMRT ILKEGPPPIK
SALEDWTTRD GLLFYKNRCY VPNKGNLRRE IVKTIHEAKG VGHPGQFNTL EQVSRDYWWP
GMAKFVKMFV DGCAKCQESK TITHPNKPPL LPIEGEKDVL PFSKITMDLI TDLPESGGYD
TILVVVDHSS TKGVIFTPCN KTIDAEQTAT LLLNNVYKRF GLPNKIISDR DPRFAAKVFQ
ELGKQLGVKH MMSTAFHPQT DGESERVNQE LEVFLRLFCS RQQDKWAEFL PFTEFAHNNR
THSTMKKSPF YLMMGYNPRP LPTVFTKTTI PSIEARLSVL KKLREETYSL MELARRKMEN
TTKRTFTPFT VGQKVWLEGK NLNFGYPSKK LAPKREGPFK IEMVLGPVTY KLALPEQWKV
HPVFHAALLS PYRRNEVHGR NFLKPPPDLV EGQEEHEVEA IIGHTPKRKP QRFLVSWKGY
PSAENEWLWE EDFEHAKETL ADYKKANKLR SILTKTTLSK CLNHSPTKTF AQPQPNSFTC
SITPLIEPGS LKQPEASPSS TISSGTTNTS SANTNTLTN
//
