ID V3YYP5_LOTGI Unreviewed; 498 AA.
AC V3YYP5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Prenylcysteine lyase domain-containing protein {ECO:0000259|Pfam:PF07156};
GN ORFNames=LOTGIDRAFT_236715 {ECO:0000313|EMBL:ESO83268.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO83268.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO83268.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the prenylcysteine oxidase family.
CC {ECO:0000256|ARBA:ARBA00009967}.
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DR EMBL; KB203738; ESO83268.1; -; Genomic_DNA.
DR RefSeq; XP_009066024.1; XM_009067776.1.
DR AlphaFoldDB; V3YYP5; -.
DR STRING; 225164.V3YYP5; -.
DR EnsemblMetazoa; LotgiT236715; LotgiP236715; LotgiG236715.
DR GeneID; 20250223; -.
DR KEGG; lgi:LOTGIDRAFT_236715; -.
DR CTD; 20250223; -.
DR HOGENOM; CLU_021176_1_0_1; -.
DR OMA; QMWVESI; -.
DR OrthoDB; 551774at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0001735; F:prenylcysteine oxidase activity; IEA:InterPro.
DR GO; GO:0030328; P:prenylcysteine catabolic process; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR010795; Prenylcys_lyase.
DR InterPro; IPR017046; Prenylcysteine_Oxase.
DR PANTHER; PTHR15944; FARNESYLCYSTEINE LYASE; 1.
DR PANTHER; PTHR15944:SF0; PRENYLCYS_LYASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13450; NAD_binding_8; 1.
DR Pfam; PF07156; Prenylcys_lyase; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..498
FT /note="Prenylcysteine lyase domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004715118"
FT DOMAIN 118..484
FT /note="Prenylcysteine lyase"
FT /evidence="ECO:0000259|Pfam:PF07156"
SQ SEQUENCE 498 AA; 56343 MW; 92A71C3CF645BEE3 CRC64;
MYFTVLLALF LVALPINYAE EEDIRIGIIG GGIGGTSTAY YLKSLFGDGC HIDLFESERV
GGRLANINID GYDYEAGGSI IHPKNKYMVE FAEKFGFKQS ASLDGKMALY GPSGIILETS
SWNFVTMAKF FWRYGMDIWN IGSFLKENFL DKFGKIYDIQ EEGLAFTTVE DLLKSMDESL
VNYTKISIQD LMIEKGFSER FINELVMGAL RTNYGQTTNV HAFVGAVSLA GVEKGLWSVK
GGNYQIPERL LKKSGANLIK AKVTHVILQK ESESVSYEVQ YQNAEDGKSN SREYDIVIVA
TPLKELEDHI KFEDFPNPIP SSYTDFHRTI ALFVQGTPNY TAYGFENAEN FPQSILTTDE
NIFWNSYGQH TPVSQKKHLN KNSDKDGDQE DNTVSKIFLN KVPTEDQVHY LFKSRKDLRL
VNWLAYPEYA PKMDLPPFVL YDQLYYVNAI ESAASAMEMS VIGGRNVANL AYNHWNNILD
KVDEFSIKKD SKSDKSEL
//
