ID V3ZLI2_LOTGI Unreviewed; 390 AA.
AC V3ZLI2;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN ORFNames=LOTGIDRAFT_236717 {ECO:0000313|EMBL:ESO83270.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO83270.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO83270.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR EMBL; KB203738; ESO83270.1; -; Genomic_DNA.
DR RefSeq; XP_009066026.1; XM_009067778.1.
DR AlphaFoldDB; V3ZLI2; -.
DR STRING; 225164.V3ZLI2; -.
DR EnsemblMetazoa; LotgiT236717; LotgiP236717; LotgiG236717.
DR GeneID; 20250225; -.
DR KEGG; lgi:LOTGIDRAFT_236717; -.
DR CTD; 20250225; -.
DR HOGENOM; CLU_708422_0_0_1; -.
DR OMA; RTEINMF; -.
DR OrthoDB; 1453590at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR CDD; cd01450; vWFA_subfamily_ECM; 2.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR22588; UNCHARACTERIZED; 1.
DR PANTHER; PTHR22588:SF3; VWFA DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..390
FT /note="VWFA domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004715305"
FT DOMAIN 33..202
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 215..384
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 390 AA; 42868 MW; 1F78BCDA480B9C63 CRC64;
MNLVAISIMV ICGVMHQSLT SPLQNGCKET PLDVIAVLDG SESITDEKFT QVKIALEQLI
RSLRLQYHDS RFGVVLYSSS VSAVLPFSNN EMDLINRIRA LEQPMEGTQT HLGLEEMNKM
FRMEGRPHAA KVGIVFTDGI SKNKVATSTA ARESIRTEIN MFSIGTSMDI NMEELQIIAS
SNDRVLSLET ISEIYNHLKG FIQSCGDIGC KDYMDVVTVV DGSDSISHTE FESVKNAVKE
FVQELSLESP LSRFSLVLFS SNVSNVIDFT HNKADLLSQI DSLEQPRDGT DTAAALEKTN
ALMNISGRQG VPKIIVVITD GYSKNSTQTI IHADEAKNMG INVFSIGITD KKQDTELVSI
ASDIDKSLVL EDFKELSKLV MEDVRKACGG
//
