ID V3ZM52_LOTGI Unreviewed; 258 AA.
AC V3ZM52;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Neurotransmitter-gated ion-channel transmembrane domain-containing protein {ECO:0000259|Pfam:PF02932};
DE Flags: Fragment;
GN ORFNames=LOTGIDRAFT_154855 {ECO:0000313|EMBL:ESO85362.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO85362.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO85362.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB203274; ESO85362.1; -; Genomic_DNA.
DR RefSeq; XP_009063611.1; XM_009065363.1.
DR AlphaFoldDB; V3ZM52; -.
DR EnsemblMetazoa; LotgiT154855; LotgiP154855; LotgiG154855.
DR GeneID; 20236431; -.
DR KEGG; lgi:LOTGIDRAFT_154855; -.
DR CTD; 20236431; -.
DR HOGENOM; CLU_1079980_0_0_1; -.
DR OMA; RAPYWLR; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:InterPro.
DR InterPro; IPR036719; Neuro-gated_channel_TM_sf.
DR InterPro; IPR006029; Neurotrans-gated_channel_TM.
DR Pfam; PF02932; Neur_chan_memb; 1.
DR SUPFAM; SSF90112; Neurotransmitter-gated ion-channel transmembrane pore; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..225
FT /note="Neurotransmitter-gated ion-channel transmembrane"
FT /evidence="ECO:0000259|Pfam:PF02932"
FT REGION 90..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 138..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..118
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ESO85362.1"
SQ SEQUENCE 258 AA; 29357 MW; E78B16D71DE4994A CRC64;
VYLCVVMTMT SVSVIVAVLV INIYNRGMKT NRAPYWLRKL TLQWLSKAIC LHHDIILVAQ
GVKLNIFTYT SMRTPDPLAA MEEKSVIESN EIKGHKNNNK DNYCSDTNFN SPSEVTLPPN
QPEKVWYRHE ELEELLRTEQ ERSQQAQLRQ TQTANKGSGS TPSNATDDPE NDNVSKPVQY
SYSIESNLSD LPHVDRKKIM IAEWQRIAAA TDRILFIIYM LATVTAYFIL LIILPTQHYS
SQKHSLSNAI LLNNGTKS
//
