ID V3ZMR0_LOTGI Unreviewed; 284 AA.
AC V3ZMR0;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Tropomyosin {ECO:0008006|Google:ProtNLM};
GN ORFNames=LOTGIDRAFT_233095 {ECO:0000313|EMBL:ESO92663.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO92663.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO92663.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- FUNCTION: Tropomyosin, in association with the troponin complex, plays
CC a central role in the calcium dependent regulation of muscle
CC contraction. {ECO:0000256|ARBA:ARBA00002987}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the tropomyosin family.
CC {ECO:0000256|ARBA:ARBA00009036, ECO:0000256|RuleBase:RU004515}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB202050; ESO92663.1; -; Genomic_DNA.
DR RefSeq; XP_009056803.1; XM_009058555.1.
DR AlphaFoldDB; V3ZMR0; -.
DR STRING; 225164.V3ZMR0; -.
DR EnsemblMetazoa; LotgiT233095; LotgiP233095; LotgiG233095.
DR GeneID; 20249151; -.
DR KEGG; lgi:LOTGIDRAFT_233095; -.
DR CTD; 20249151; -.
DR HOGENOM; CLU_055027_0_2_1; -.
DR OMA; EEMDHAP; -.
DR OrthoDB; 2917119at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR Gene3D; 1.20.5.170; -; 2.
DR Gene3D; 1.20.5.340; -; 1.
DR InterPro; IPR000533; Tropomyosin.
DR PANTHER; PTHR19269; TROPOMYOSIN; 1.
DR PANTHER; PTHR19269:SF45; TROPOMYOSIN-1, ISOFORMS 33_34; 1.
DR Pfam; PF00261; Tropomyosin; 1.
DR PRINTS; PR00194; TROPOMYOSIN.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS00326; TROPOMYOSIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 107..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 284 AA; 32683 MW; 0B7AC59B67A8471E CRC64;
MDAIKKKMLA MKMEKENALD RAEQLEQKLR DTEEQKSKIE EDLNTLQKKY ANLENDFDTA
NESLAEANTK LEVSEKKANE LETEAAGFTR RITLLEEDLE RSEERLTSAQ SKLEEASKAA
DESERGRKVL ESRSLSDDER IDQLEAQLKE AKYIAEDAER KYDEAARKLA ITEVDLERAE
TRLEAAEAKI YELDEELHVV GNNLKTYTVK VSEASQREDS YEETIRDLTN RLKEAENRAT
EAERTVSKLQ KEVDRLEDEL LAEKEKYKAI SDELDSTFAE LAGY
//
