ID   V3ZPR4_LOTGI            Unreviewed;      1427 AA.
AC   V3ZPR4;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=Death domain-containing protein {ECO:0000259|PROSITE:PS50017};
GN   ORFNames=LOTGIDRAFT_232757 {ECO:0000313|EMBL:ESO93353.1};
OS   Lottia gigantea (Giant owl limpet).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX   NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO93353.1, ECO:0000313|Proteomes:UP000030746};
RN   [1] {ECO:0000313|EMBL:ESO93353.1, ECO:0000313|Proteomes:UP000030746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23254933; DOI=10.1038/nature11696;
RA   Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA   Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA   Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA   Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA   Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT   "Insights into bilaterian evolution from three spiralian genomes.";
RL   Nature 493:526-531(2013).
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DR   EMBL; KB201931; ESO93353.1; -; Genomic_DNA.
DR   RefSeq; XP_009056048.1; XM_009057800.1.
DR   EnsemblMetazoa; LotgiT232757; LotgiP232757; LotgiG232757.
DR   GeneID; 20249038; -.
DR   KEGG; lgi:LOTGIDRAFT_232757; -.
DR   CTD; 20249038; -.
DR   HOGENOM; CLU_252721_0_0_1; -.
DR   OMA; AFNSHIN; -.
DR   OrthoDB; 5312372at2759; -.
DR   Proteomes; UP000030746; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01670; Death; 1.
DR   Gene3D; 2.60.220.30; -; 2.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 2.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_domain.
DR   PANTHER; PTHR28336; BA1-643; 1.
DR   PANTHER; PTHR28336:SF4; DEATH DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00531; Death; 2.
DR   SMART; SM00005; DEATH; 2.
DR   SUPFAM; SSF47986; DEATH domain; 2.
DR   PROSITE; PS50017; DEATH_DOMAIN; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000030746}.
FT   DOMAIN          1240..1326
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
FT   DOMAIN          1358..1427
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
FT   REGION          142..216
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          255..275
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          289..340
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          353..393
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          649..713
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          947..977
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        148..166
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        167..205
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        305..340
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        364..384
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1427 AA;  163042 MW;  DC308A4106B52FF0 CRC64;
     MSGGDLHINH NQWDYLYNDT EQSDICLNNR QSIDHDINHL TFDHVSPSIS TQQNPPLVTN
     ENAFNYHTRS NEISSNVSDT YESFLKEGDL GLDEYNISDS PDFASPGTKN RYTHDSGCDY
     IQTGIEEDLP WLGENRLSQI SEDSAGEISD DSNQEDADEN ESKCLDTESE EVDQRKSSHR
     NLDELSESFE VKVNDEARED NISTQPKAKE YSSNYRSTIR KSQKSVSFQD SVGIIDDSES
     DELELIFSEK SFSFEENGSL VSDTSHQDID GEDQQDVFDA STLRSESLDI YTDDHVDEYD
     SDWENYSSDG GSTLGSQRSR SSTSGSTVTN HNTDNSDSLD SFTTSFIPTY LDNQSTDFDS
     QPTEVDSKPI DFDSQQKEVD SKATDFDSQP TNEQPSYIES IAKEFRGTPS KDFYTFDNSR
     TLALYPDENG SDWKRPVSAK MTSREEVVNM EPNSLSMSKS FCQEVKYGNQ NVVSLQISLQ
     NIFQKSGHIL GQYKEKLSTE QLKDFALNLT DFHESFVALS ELFASCESLS QVINKDLKDI
     RHVTDDVCNL INRKFRDEDL VTWVDHTEKD HQEKERLEEE RIATDKALLA KAAEARASSA
     KAVTIIAETD KIIADSETEA VEAELAAKRA RELADDVIKA AEDARRAAEE RRKAEMEAKR
     RADEKARVKA EEERQKKEEE TKRIEAEARK RGTSFDVEKS REEEEKRKRE AERKNPNNWP
     RYIYSIESED FNPGIGCIIR SIKGSLDRDD IEVNRIDQIT GGYQIHENEE LISNIIVVKQ
     MTDKNLEFEE PLSIVMPHCA PRSTTGREPV MKCYDDTAAN WVELQTNDVM FDDIKDLRFV
     EARVTKLGKF VVVYRLKKEQ FTFTKKGGKQ SSTVDSRFTL TTKPGAFRYN LGVSTEIQPV
     DSNTVSELRQ RDNEICGALL ASTSIITMTW KQNTRLSKPI TITLPCPPNP ARIKRPSTAV
     NREKVAKQDA RPQTARPASE YFKHTDDAKL EEELHLVIKD NTSGWLTVPD VVITQAKNKD
     IISLDITEPI TRFVVLRTKM DLAEYQAEKM VSRLEKALLQ RTIQLFLRQN TEDLNEILVS
     CANTNKIEKV LKRLDEEGYD EGPPLSKDII VREGQVLELR FRGNLAPVTE HRTKIAFNSH
     INSQITFRVE ELDKFAQRGF DSYRGFCQVF TDGLVPKVIQ EQEERDTGKG RNNPKNTHVE
     MVEGEILLGE LLMNIPKPEP EPPRPLVKAP VSIKPEGPVN EDVFRFISRE VGDEWRKLAQ
     YLNVRRMRIQ AILRQNVNSE RQQTIYDMLV SWAKRVPRAM DKVEMLCHAL SVCGRGDLVE
     ILRERNMEFK REKAFSAKDS YLRKAFIKIS RDEKVSGNWK VLAKGLGLTD QTLRDIEGSR
     PTRQDRCFYS LQKWRDIKDS EATIPNLSQK LRECRYRVLA REVEAIG
//