ID V3ZWC8_LOTGI Unreviewed; 418 AA.
AC V3ZWC8;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=BAAT/Acyl-CoA thioester hydrolase C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=LOTGIDRAFT_125734 {ECO:0000313|EMBL:ESO88692.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO88692.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO88692.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SIMILARITY: Belongs to the C/M/P thioester hydrolase family.
CC {ECO:0000256|ARBA:ARBA00006538}.
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DR EMBL; KB202656; ESO88692.1; -; Genomic_DNA.
DR RefSeq; XP_009060740.1; XM_009062492.1.
DR AlphaFoldDB; V3ZWC8; -.
DR STRING; 225164.V3ZWC8; -.
DR EnsemblMetazoa; LotgiT125734; LotgiP125734; LotgiG125734.
DR GeneID; 20232533; -.
DR KEGG; lgi:LOTGIDRAFT_125734; -.
DR CTD; 20232533; -.
DR HOGENOM; CLU_029849_4_0_1; -.
DR OMA; FEEAAHW; -.
DR OrthoDB; 5356064at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR GO; GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 2.60.40.2240; Acyl-CoA thioester hydrolase/BAAT N-terminal domain; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR016662; Acyl-CoA_thioEstase_long-chain.
DR InterPro; IPR014940; BAAT_C.
DR InterPro; IPR006862; Thio_Ohase/aa_AcTrfase.
DR InterPro; IPR042490; Thio_Ohase/BAAT_N.
DR PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR PANTHER; PTHR10824:SF4; PROTEIN CBG14567; 1.
DR Pfam; PF08840; BAAT_C; 1.
DR Pfam; PF04775; Bile_Hydr_Trans; 1.
DR PIRSF; PIRSF016521; Acyl-CoA_hydro; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030746}.
FT DOMAIN 14..147
FT /note="Acyl-CoA thioester hydrolase/bile acid-CoA amino
FT acid N-acetyltransferase"
FT /evidence="ECO:0000259|Pfam:PF04775"
FT DOMAIN 209..412
FT /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08840"
FT ACT_SITE 238
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT ACT_SITE 327
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT ACT_SITE 360
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
SQ SEQUENCE 418 AA; 46126 MW; D835B9393D79CB55 CRC64;
MSISVSQTDS LMDDIISVKI TELKPHKLVT LSAQIKEKPS EIFISNGWYK ADNNGDVDLA
KDASLNGTYT GINPMGFLSS MVSGCDSDGT LALHKSDVTQ PHKVELCVYD GHKLLKELLS
EALKPISSIV INRWYLKPNV RRLEVNEGKI RGTLFIPAGN STHPGIIDLY GSSGRLKETR
AALLASRGFT TLALAYFQYL DLPSTLAEVD FSYFEEAVSW FKHHHNVQPG GVGVVGLSKG
GEFANLMARY IPDIKCIVNI NGAPFLSFFN LKRNGKLFQK AVEIDSSNIL VENNAFTLKN
AYQCCNSDII PLWETKVKTL VITGQDDRQN NSEFYQNLSD LYPSDRKENL TILSYPNAGH
LIQPPFTPLT TSTYGANFSG IILVNGGTNP GHSHAQTGAW KKMLKFLNEN LNTSKSQL
//
