ID V3ZYE7_LOTGI Unreviewed; 286 AA.
AC V3ZYE7;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Nucleoside phosphorylase domain-containing protein {ECO:0000259|Pfam:PF01048};
GN ORFNames=LOTGIDRAFT_159977 {ECO:0000313|EMBL:ESO96558.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO96558.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO96558.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SIMILARITY: Belongs to the PNP/UDP phosphorylase family.
CC {ECO:0000256|ARBA:ARBA00010456}.
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DR EMBL; KB201459; ESO96558.1; -; Genomic_DNA.
DR RefSeq; XP_009052911.1; XM_009054663.1.
DR AlphaFoldDB; V3ZYE7; -.
DR STRING; 225164.V3ZYE7; -.
DR EnsemblMetazoa; LotgiT159977; LotgiP159977; LotgiG159977.
DR GeneID; 20238238; -.
DR KEGG; lgi:LOTGIDRAFT_159977; -.
DR CTD; 20238238; -.
DR HOGENOM; CLU_054104_0_0_1; -.
DR OMA; AVCEYSE; -.
DR OrthoDB; 22073at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004850; F:uridine phosphorylase activity; IEA:InterPro.
DR GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
DR GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR CDD; cd17763; UP_hUPP-like; 1.
DR Gene3D; 3.40.50.1580; Nucleoside phosphorylase domain; 1.
DR InterPro; IPR000845; Nucleoside_phosphorylase_d.
DR InterPro; IPR035994; Nucleoside_phosphorylase_sf.
DR InterPro; IPR010059; Uridine_phosphorylase_euk.
DR NCBIfam; TIGR01719; euk_UDPppase; 1.
DR PANTHER; PTHR43691:SF11; FI09636P-RELATED; 1.
DR PANTHER; PTHR43691; URIDINE PHOSPHORYLASE; 1.
DR Pfam; PF01048; PNP_UDP_1; 1.
DR SUPFAM; SSF53167; Purine and uridine phosphorylases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030746}.
FT DOMAIN 37..283
FT /note="Nucleoside phosphorylase"
FT /evidence="ECO:0000259|Pfam:PF01048"
FT BINDING 75
FT /ligand="phosphate"
FT /ligand_id="ChEBI:CHEBI:43474"
FT /evidence="ECO:0000256|PIRSR:PIRSR610059-50"
FT BINDING 119..122
FT /ligand="phosphate"
FT /ligand_id="ChEBI:CHEBI:43474"
FT /evidence="ECO:0000256|PIRSR:PIRSR610059-50"
FT BINDING 196
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR610059-50"
FT BINDING 198
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR610059-50"
SQ SEQUENCE 286 AA; 32196 MW; 473D9B73C8B94E7E CRC64;
MELKTNPHIK LNADDYLYHL DLETSKLDFK KEFNDVKFVC IGGSPTRMLN FAKFMSKQLT
GNTEEPRNYA KGTDRYCLYK AGPVLIANHG IGTASLSVVL NELFKLLFYA QCSNVIFLRL
GTCGGIGVEG GTVVITDKAV NGELEPIFSY MKLGKRINSP TYVDSDLVNE IYNCCKDNFN
VARGTTCSVD CFYEAQGRLD GALCDYFEND KQDFIKRLQD KGVINMEMEG LGLFSYCHRA
GFKAAMIAVT IVNRLVEDVP TSEIDVIKEW EERPFKVALQ FIRSKL
//
