ID V3ZZP4_LOTGI Unreviewed; 75 AA.
AC V3ZZP4;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=TNFR-Cys domain-containing protein {ECO:0000259|PROSITE:PS50050};
DE Flags: Fragment;
GN ORFNames=LOTGIDRAFT_88625 {ECO:0000313|EMBL:ESO88140.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO88140.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO88140.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; KB202752; ESO88140.1; -; Genomic_DNA.
DR RefSeq; XP_009061167.1; XM_009062919.1.
DR AlphaFoldDB; V3ZZP4; -.
DR EnsemblMetazoa; LotgiT88625; LotgiP88625; LotgiG88625.
DR GeneID; 20252797; -.
DR KEGG; lgi:LOTGIDRAFT_88625; -.
DR CTD; 20252797; -.
DR HOGENOM; CLU_156806_0_0_1; -.
DR OrthoDB; 2967907at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR PANTHER; PTHR23097; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER; 1.
DR PANTHER; PTHR23097:SF181; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 21-LIKE-RELATED; 1.
DR Pfam; PF00020; TNFR_c6; 1.
DR SMART; SM00208; TNFR; 1.
DR SUPFAM; SSF57586; TNF receptor-like; 2.
DR PROSITE; PS00652; TNFR_NGFR_1; 1.
DR PROSITE; PS50050; TNFR_NGFR_2; 1.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00206}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 25..65
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 25..65
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 26..41
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 44..57
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 47..65
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ESO88140.1"
FT NON_TER 75
FT /evidence="ECO:0000313|EMBL:ESO88140.1"
SQ SEQUENCE 75 AA; 8559 MW; 008BE5B8C263BB13 CRC64;
CQWCPVGEFL VTQCERDREA SICETCPEKQ FRDKPNNKTC CNDCTFCALG KEIVKNCTKT
SDTVCKCPPG KHWHD
//
