ID V4A0S0_LOTGI Unreviewed; 558 AA.
AC V4A0S0;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESO97393.1};
GN ORFNames=LOTGIDRAFT_231570 {ECO:0000313|EMBL:ESO97393.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO97393.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO97393.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; KB201305; ESO97393.1; -; Genomic_DNA.
DR RefSeq; XP_009051986.1; XM_009053738.1.
DR AlphaFoldDB; V4A0S0; -.
DR STRING; 225164.V4A0S0; -.
DR EnsemblMetazoa; LotgiT231570; LotgiP231570; LotgiG231570.
DR GeneID; 20248638; -.
DR KEGG; lgi:LOTGIDRAFT_231570; -.
DR CTD; 20248638; -.
DR HOGENOM; CLU_017959_5_4_1; -.
DR OMA; AHANSEM; -.
DR OrthoDB; 2878254at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR11119:SF118; SOLUTE CARRIER FAMILY 23 MEMBER 2; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 2.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 419..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 450..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 558 AA; 60130 MW; F907D74793C3C710 CRC64;
MDKTDREADE RNRASTVLYG VSDIPPWHIT LLLGCQVFLT CLGGTFAYPL IISGALCLEG
DTLGLAQVIG TVIFVSGLST LIQTFFGIRL PIVQSCSPAF ITPVFSLMAI YKPTDCPFNI
KNYNETLPEI GGPVHREIWQ TRIIEVTGAI MIASLFQLVI GCSGLLGVML RFIGPLTVTP
TIAMIGLSIF NPAYQKSENQ WWIAITTVAL IVIFSQYIML AIVTAWVICI ILTASGALPD
DKNGWGYKAR TDVKIAVLEK ADWFRFPYPG QWGMPTISLA GVFGMLAGVF ATIVESVGDY
YACARLANAP PPPGSAVSRG IGMEGVACVI GAGIGSPGCT TSYSENIGAI GITKVGSRIV
TQVGAVIMLF LGCFTKFGAL FVTLPDSIVG GLFFVMFGMV TAVGLSNLQF VNLNSSRNLF
VIGVPLVFAL SVPTWLKIQS SSPISTGSVF VDQIFTVLLS TNMFVAGLLA FFLDNTIPGS
DEERGIKAWR ETDKHDSDDG SSSHVYDIPF LQKYLDKLAC SKYVPILPNF KGDKSDSTVT
GCCKQCRSPS FKEPEVYV
//
