ID V4A3L0_LOTGI Unreviewed; 250 AA.
AC V4A3L0;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Protein twisted gastrulation {ECO:0008006|Google:ProtNLM};
GN ORFNames=LOTGIDRAFT_231460 {ECO:0000313|EMBL:ESO98443.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO98443.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO98443.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the twisted gastrulation protein family.
CC {ECO:0000256|ARBA:ARBA00010047}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB201262; ESO98443.1; -; Genomic_DNA.
DR RefSeq; XP_009051127.1; XM_009052879.1.
DR AlphaFoldDB; V4A3L0; -.
DR STRING; 225164.V4A3L0; -.
DR EnsemblMetazoa; LotgiT231460; LotgiP231460; LotgiG231460.
DR GeneID; 20248597; -.
DR KEGG; lgi:LOTGIDRAFT_231460; -.
DR CTD; 20248597; -.
DR HOGENOM; CLU_082511_1_0_1; -.
DR OMA; CECIGDT; -.
DR OrthoDB; 2896997at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR006761; Tsg.
DR PANTHER; PTHR12312:SF16; TWISTED GASTRULATION PROTEIN HOMOLOG 1; 1.
DR PANTHER; PTHR12312; TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED; 1.
DR Pfam; PF04668; Tsg; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..250
FT /note="Protein twisted gastrulation"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004716341"
SQ SEQUENCE 250 AA; 27805 MW; B80F97AE29E0F69C CRC64;
MGLIKEVIVT VLSILAIVLL SEACNEDICG PQVSKCMLIK CCECDMSDKK NCTCCNDCQV
CLSKFYTECC DCVGLCAKQD PHDTPRKTSS VEDLIDPIPD LFKVLTEQVD RLMRWTSKSY
PALSEVFTKP SGNNMDTSST FDVGKSLEKA IEEELLSKQN CTVAFMSQCM SIRKCKLSCK
SMGAAKYRWF HDNACCECIS STCYDYGLNQ PQCLKCPLDD ELLELELAEG VKNEGAGQML
SAVERMMDKV
//
