ID   V4AB23_LOTGI            Unreviewed;       897 AA.
AC   V4AB23;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
GN   ORFNames=LOTGIDRAFT_175708 {ECO:0000313|EMBL:ESO92295.1};
OS   Lottia gigantea (Giant owl limpet).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX   NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO92295.1, ECO:0000313|Proteomes:UP000030746};
RN   [1] {ECO:0000313|EMBL:ESO92295.1, ECO:0000313|Proteomes:UP000030746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23254933; DOI=10.1038/nature11696;
RA   Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA   Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA   Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA   Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA   Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT   "Insights into bilaterian evolution from three spiralian genomes.";
RL   Nature 493:526-531(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR   EMBL; KB202096; ESO92295.1; -; Genomic_DNA.
DR   RefSeq; XP_009057022.1; XM_009058774.1.
DR   AlphaFoldDB; V4AB23; -.
DR   EnsemblMetazoa; LotgiT175708; LotgiP175708; LotgiG175708.
DR   GeneID; 20243346; -.
DR   KEGG; lgi:LOTGIDRAFT_175708; -.
DR   CTD; 20243346; -.
DR   HOGENOM; CLU_322688_0_0_1; -.
DR   OrthoDB; 3033616at2759; -.
DR   Proteomes; UP000030746; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 6.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003006; Ig/MHC_CS.
DR   InterPro; IPR013098; Ig_I-set.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   PANTHER; PTHR11640:SF164; MAM DOMAIN-CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR PROTEIN 1; 1.
DR   PANTHER; PTHR11640; NEPHRIN; 1.
DR   Pfam; PF07679; I-set; 1.
DR   Pfam; PF13927; Ig_3; 1.
DR   SMART; SM00409; IG; 7.
DR   SMART; SM00408; IGc2; 5.
DR   SUPFAM; SSF48726; Immunoglobulin; 5.
DR   PROSITE; PS50835; IG_LIKE; 6.
DR   PROSITE; PS00290; IG_MHC; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        623..642
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          14..116
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          121..195
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          213..304
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          411..493
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          498..585
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          754..828
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
SQ   SEQUENCE   897 AA;  99390 MW;  72D3060B594F3ABD CRC64;
     MEYKCILIVI VYLPVLITGQ YTIRGIPESY AELGENYTLQ CNVTDSPSVL DFRRNNIVVC
     NMINCESSST DNRYKCGCIN NNNKQLYLNI SNINKQDDTT WSCRGNSGGQ GSSNVSVYYG
     PENIRFNPTS DNIDVIEGKS QSVNCLADCK PDCHITWSKD GSTTILNNTL SLSTRDQTGS
     YNCTVKHTVL NKQLTKQLNV QIYYGRDELA FSPDVTSINI IEDGPDELAF SADVTSNNII
     EGRDQTIICL TDCYQCNYKW TGPVSSPTKD LVFTQIKRNQ EGNYRCEATN IKNTIPKTRS
     KSIQINVHCQ YTIRGVPESY AVLGENYTLQ CDVTPSSVEF RINNIVVCNI LSSTCESQST
     DNRYKCGCIN NNNTQLYLSI SNINNQDDTT WSCNGNSGGQ GSINVSVYYP PYITSIISDA
     VNNEIDEGSD VIFNCNVDSK PVSTITWSSS TSTDSNTGQQ WTLAQAKCQD TGIYTCTANN
     GIGQSTTKSL PLNIRCSPRI NGDLKDEVMN RLGEEVTLSI DVIAYPKPSF NWIQESTGQE
     LTPDTAQQVA INNYISSLTI IIQQSSFGNY IVTVNNSIGD DKSYTIKIID GDPGTKPVSV
     EQSGYQKGLS TGIGTGIGIG IDIGIGITLV CVFLVLLTIF IYRKYHPANR KLPEENHYIV
     TLSTTDWFGR IEKFKSLYHY ISYATFSNRN PEGQYTIRGV PESYAVFGEN YTLQCTVTDS
     PSLVDFRGNN DVVCTMINCG SQPIDNRYKC RYGPENIKFN PTCDNIDVTE GKNQSVKCLA
     DCKPDCNITW SKDGSPTILN NPLSLSTSDQ TGSYTCTVRH TVLNKQLTKQ LNVQIYYGPD
     KLTFSPDVSR INIIEGRDQT ITYGPDELTF SSDVTSINII EDGPDELTFS SDVTSIK
//