ID V4AGK0_LOTGI Unreviewed; 282 AA.
AC V4AGK0;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 08-NOV-2023, entry version 33.
DE RecName: Full=U1-type domain-containing protein {ECO:0000259|SMART:SM00451};
DE Flags: Fragment;
GN ORFNames=LOTGIDRAFT_137805 {ECO:0000313|EMBL:ESP03169.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESP03169.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESP03169.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ANKZF1/VMS1 family.
CC {ECO:0000256|ARBA:ARBA00009262}.
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DR EMBL; KB200084; ESP03169.1; -; Genomic_DNA.
DR RefSeq; XP_009046092.1; XM_009047844.1.
DR AlphaFoldDB; V4AGK0; -.
DR STRING; 225164.V4AGK0; -.
DR EnsemblMetazoa; LotgiT137805; LotgiP137805; LotgiG137805.
DR GeneID; 20233951; -.
DR KEGG; lgi:LOTGIDRAFT_137805; -.
DR CTD; 20233951; -.
DR HOGENOM; CLU_045603_0_0_1; -.
DR OMA; RANERHL; -.
DR OrthoDB; 8371at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR InterPro; IPR047139; ANKZ1/VMS1.
DR InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR InterPro; IPR041175; VLRF1/Vms1.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR PANTHER; PTHR16036; ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR16036:SF2; ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF18826; bVLRF1; 1.
DR SMART; SM00451; ZnF_U1; 1.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 2..36
FT /note="U1-type"
FT /evidence="ECO:0000259|SMART:SM00451"
FT REGION 57..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 167..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ESP03169.1"
SQ SEQUENCE 282 AA; 32803 MW; 56FF5E3571345032 CRC64;
VSDKMYCNCC ECTFEDRKEQ EQHYKSDWHR YNLRLRLGGF KTVKIEDFEK IANDVSSISG
SEDEGERTSD EETECQSKKT KNSKHQMNKI YLKTKDGELI SLYRCLLYHK KNRLTEQTDL
IEEIKKLPQK TNSAIFMSAG GHFAGAIYNG KQVLTHKTFH RYVVRAKRGT AQSSRDSQGG
NAPKSAGASL RRYNEAALIQ EIQDWIMNNG EVINTCDFLF LRAPSFNRKI FYGGKNPPFT
KDDDRIRVIP FPTRRPTYNE VKRVYEMLFS IECYGRHILY IT
//
